A Messer
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Explore the profile of A Messer including associated specialties, affiliations and a list of published articles.
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Articles
68
Citations
865
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Recent Articles
1.
Butler D, Snyder-Keller A, De Genst E, Messer A
Protein Eng Des Sel
. 2014 Oct;
27(10):359-63.
PMID: 25301961
Intrabodies offer attractive options for manipulating the protein misfolding that triggers neurodegenerative diseases. In Huntington's disease, where the expanded polyglutamine tract in the extreme N-terminal region of huntingtin exon1 misfolds,...
2.
Messer A, Snodgrass G, Maskin P
Int J Dev Neurosci
. 2014 May;
3(3):291-9.
PMID: 24874757
Dissociated cells from week-old mouse cerebellum were grown on either polylysine coated coverslips or on uncoated coverslips. Polylysine coated coverslips give rise to cultures containing all of the cerebellar cell...
3.
Messer A, Maskin P, Snodgrass G
Int J Dev Neurosci
. 2014 May;
2(3):277-85.
PMID: 24874042
To determine whether or not the effects of thyroxine on the cells of the external granular layer of rat cerebellum are direct or indirect, Purkinje cell-free dissociated cell cultures from...
4.
Messer A, McCormick K, Sunjaya , Hagedorn H, Tumbel F, Meinwald J
J Chem Ecol
. 2013 Nov;
16(12):3333-52.
PMID: 24263433
Chemical components demonstrating antiinsectan properties were isolated and identified from crude resins of fourDipterocarpus species. The most active compounds against Southeast Asian termites (Neotermes spp.) proved to be alloaromadendrene, humulene,...
5.
Bortvedt S, McLear J, Messer A, Ahern-Rindell A, Wolfgang W
Neurobiol Dis
. 2010 Apr;
40(1):130-4.
PMID: 20399860
Huntington's disease (HD) is a lethal, neurodegenerative disorder caused by expansion of the polyglutamine repeat in the Huntingtin gene (HTT), leading to mutant protein misfolding, aggregation, and neuronal death. Feeding...
6.
Messer A
Neurosci Lett
. 2009 Jul;
9(2-3):185-8.
PMID: 19605215
Staggerer cerebellar cells in primary monolayer cell culture exhibit less initial clumping and unexpectedly longer overall survival than their wild-type counterparts when grown in medium containing fetal calf serum. Although...
7.
McLear J, Lebrecht D, Messer A, Wolfgang W
FASEB J
. 2008 Jan;
22(6):2003-11.
PMID: 18199697
Intracellular antibodies (intrabodies) and the chaperone, heat shock protein 70 (Hsp70), have each shown potential as therapeutics for neurodegenerative diseases in vitro and in vivo. Investigating combinational therapy in an...
8.
Jubinsky P, Messer A, Bender J, Morris R, Ciraolo G, Witte D, et al.
Exp Hematol
. 2001 Dec;
29(12):1392-402.
PMID: 11750097
Objective: The aim of this study was to identify granulocyte-macrophage colony-stimulating factor (GM-CSF) responsive genes. Materials And Methods: Potential GM-CSF responsive genes were identified by comparing the mRNA expression pattern...
9.
Kang X, Messer A
Brain Res Bull
. 2001 Nov;
56(3-4):307-12.
PMID: 11719265
Huntington's disease (HD) is an inherited neurodegenerative disorder resulting in neuronal cell death in discrete brain regions due to an expanded CAG repeat of the huntingtin gene. The transgenic mouse...
10.
Lecerf J, Shirley T, Zhu Q, Kazantsev A, Amersdorfer P, Housman D, et al.
Proc Natl Acad Sci U S A
. 2001 Apr;
98(8):4764-9.
PMID: 11296304
This investigation was pursued to test the use of intracellular antibodies (intrabodies) as a means of blocking the pathogenesis of Huntington's disease (HD). HD is characterized by abnormally elongated polyglutamine...