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» Authors » A M ODoherty

A M ODoherty

Explore the profile of A M ODoherty including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 104
Followers 0
Related Specialties
Genetics
Reproductive Medicine
Oncology
Top 10 Co-Authors
P Lonergan
T Fair
N Forde
J Nelson
M Di Fenza
M A Crowe
P M Strappe
E Fournier
L C OShea
M A Sirard
Published In
Br J Cancer
Sci Rep
Reproduction
Gene Ther
Reprod Fertil Dev
Affiliations
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Recent Articles
1.
Epigenetic reprogramming during spermatogenesis and male factor infertility
McSwiggin H, ODoherty A
Reproduction . 2018 May; 156(2):R9-R21. PMID: 29717022
Infertility is an often devastating diagnosis encountered by around one in six couples who are trying to conceive. Moving away from the long-held belief that infertility is primarily a female...
2.
Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts
Desmet K, van Hoeck V, Gagne D, Fournier E, Thakur A, ODoherty A, et al.
BMC Genomics . 2016 Dec; 17(1):1004. PMID: 27931182
Background: Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved...
3.
Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle
ODoherty A, OShea L, Sandra O, Lonergan P, Fair T, Forde N
Reprod Fertil Dev . 2016 Sep; 29(9):1729-1738. PMID: 27651295
The endometrium plays a key role in providing an optimal environment for attachment of the preimplantation embryo during the early stages of pregnancy. Investigations over the past 2 decades have...
4.
Lipopolysaccharide (LPS) disrupts particle transport, cilia function and sperm motility in an ex vivo oviduct model
ODoherty A, Di Fenza M, Kolle S
Sci Rep . 2016 Apr; 6:24583. PMID: 27079521
The oviduct functions in the transportation of gametes to the site of fertilization (the ampulla) and is the site of early embryonic development. Alterations of this early developmental environment, such...
5.
Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle
Okumu L, Fair T, Szekeres-Bartho J, ODoherty A, Crowe M, Roche J, et al.
Physiol Genomics . 2011 May; 43(14):903-10. PMID: 21610087
Progesterone-induced blocking factor (PIBF) and galectins modulate the maternal immune response during pregnancy. We hypothesized that the relative transcript abundance of the above genes would be different during the luteal...
6.
Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques
Duffy A, ODoherty A, OBrien T, Strappe P
Gene Ther . 2005 Oct; 12 Suppl 1:S62-72. PMID: 16231057
Adenovirus (Ad) and Adeno-associated virus (AAV) are efficient gene delivery systems; manipulation of the wild-type genome allows their use as vectors for the overexpression of desirable transgenes. Generation and purification...
7.
Methylation status of oestrogen receptor-alpha gene promoter sequences in human ovarian epithelial cell lines
ODoherty A, Church S, Russell S, Nelson J, Hickey I
Br J Cancer . 2002 Mar; 86(2):282-4. PMID: 11870520
We have determined the methylation status of the CpG island of the oestrogen receptor alpha gene in seven human ovarian cell lines. Cell lines expressing oestrogen receptor alpha showed no...