A M Mercurio
Overview
Explore the profile of A M Mercurio including associated specialties, affiliations and a list of published articles.
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74
Citations
2699
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Recent Articles
1.
Samanta S, Sun H, Goel H, Pursell B, Chang C, Khan A, et al.
Oncogene
. 2015 May;
35(9):1111-21.
PMID: 25982283
IMP3 (insulin-like growth factor-2 mRNA binding protein 3) is an oncofetal protein whose expression is prognostic for poor outcome in several cancers. Although IMP3 is expressed preferentially in triple-negative breast...
2.
Barney L, Dandley E, Jansen L, Reich N, Mercurio A, Peyton S
Integr Biol (Camb)
. 2014 Dec;
7(2):198-212.
PMID: 25537447
Breast cancer preferentially spreads to the bone, brain, liver, and lung. The clinical patterns of this tissue-specific spread (tropism) cannot be explained by blood flow alone, yet our understanding of...
3.
Samanta S, Sharma V, Khan A, Mercurio A
Oncogene
. 2012 Jan;
31(44):4689-97.
PMID: 22266872
Insulin-like growth factor II (IGF-II) mRNA-binding protein 3 (IMP3) is emerging as a useful indicator of the progression and outcome of several cancers. IMP3 expression is associated with triple-negative breast...
4.
Bellovin D, Simpson K, Danilov T, Maynard E, Rimm D, Oettgen P, et al.
Oncogene
. 2006 May;
25(52):6959-67.
PMID: 16715134
Understanding how RhoC expression and activation are regulated is essential for deciphering its contribution to tumorigenesis. Here, we report that RhoC expression and activation are induced by the epithelial to...
5.
Rabinovitz I, Gipson I, Mercurio A
Mol Biol Cell
. 2001 Dec;
12(12):4030-43.
PMID: 11739798
The integrin alpha6beta4, a laminin receptor that stabilizes epithelial cell adhesion to the basement membrane (BM) through its association with cytokeratins, can stimulate the formation and stabilization of actin-rich protrusions...
6.
OConnor K, Mercurio A
J Biol Chem
. 2001 Oct;
276(51):47895-900.
PMID: 11606581
Members of the Rho family of small GTPases, such as Rho and Rac, are required for actin cytoskeletal reorganization during the migration of carcinoma cells. Phosphodiesterases are necessary for this...
7.
Mercurio A, Bachelder R, Chung J, OConnor K, Rabinovitz I, Shaw L, et al.
J Mammary Gland Biol Neoplasia
. 2001 Sep;
6(3):299-309.
PMID: 11547899
This review explores the mechanistic basis of breast carcinoma progression by focusing on the contribution of integrins. Integrins are essential for progression not only for their ability to mediate physical...
8.
Mercurio A, Rabinovitz I, Shaw L
Curr Opin Cell Biol
. 2001 Sep;
13(5):541-5.
PMID: 11544021
Although the involvement of alpha 6 beta 4, an integrin laminin receptor, in hemidesmosome organization has dominated the study of this integrin, recent studies are revealing novel functions for alpha...
9.
Tani T, Mercurio A
J Biol Chem
. 2001 Aug;
276(39):36535-42.
PMID: 11479315
We used published peptide library data to identify PDZ recognition sequences in integrin alpha subunit cytoplasmic domains and found that the alpha(6)A and alpha(5) subunits contain a type I PDZ...
10.
Bachelder R, Crago A, Chung J, Wendt M, Shaw L, Robinson G, et al.
Cancer Res
. 2001 Aug;
61(15):5736-40.
PMID: 11479209
We identify a novel function for the vascular endothelial growth factor (VEGF) in its ability to stimulate an autocrine signaling pathway in metastatic breast carcinoma cells that is essential for...