A M Lambowitz
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Explore the profile of A M Lambowitz including associated specialties, affiliations and a list of published articles.
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129
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3899
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Recent Articles
1.
Collins R, Lambowitz A
Curr Genet
. 2013 Nov;
4(2):131-3.
PMID: 24185958
We have identified a second variant of Neurospora mtDNA which contains tandem, head-to-tail repeats of sequences at the boundary of Eco RI-4 and 6. This region may contain a. major...
2.
Matsuura M, NOAH J, Lambowitz A
EMBO J
. 2001 Dec;
20(24):7259-70.
PMID: 11743002
Mobile group II introns encode reverse transcriptases that also function as intron-specific splicing factors (maturases). We showed previously that the reverse transcriptase/maturase encoded by the Lactococcus lactis Ll.LtrB intron has...
3.
Karberg M, Guo H, Zhong J, COON R, Perutka J, Lambowitz A
Nat Biotechnol
. 2001 Dec;
19(12):1162-7.
PMID: 11731786
Mobile group II introns can be retargeted to insert into virtually any desired DNA target. Here we show that retargeted group II introns can be used for highly specific chromosomal...
4.
Dickson L, Huang H, Liu L, Matsuura M, Lambowitz A, Perlman P
Proc Natl Acad Sci U S A
. 2001 Nov;
98(23):13207-12.
PMID: 11687644
Group II introns, the presumed ancestors of nuclear pre-mRNA introns, are site-specific retroelements. In addition to "homing" to unoccupied sites in intronless alleles, group II introns transpose at low frequency...
5.
Singh N, Lambowitz A
J Mol Biol
. 2001 May;
309(2):361-86.
PMID: 11371159
Group II intron mobility occurs by a target DNA-primed reverse transcription mechanism in which the intron RNA reverse splices directly into one strand of a double-stranded DNA target site, while...
6.
Caprara M, Myers C, Lambowitz A
J Mol Biol
. 2001 May;
308(2):165-90.
PMID: 11327760
The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) functions in splicing group I introns by promoting the formation of the catalytically active structure of the intron's catalytic core. Previous studies...
7.
Mohr G, Rennard R, Cherniack A, Stryker J, Lambowitz A
J Mol Biol
. 2001 Mar;
307(1):75-92.
PMID: 11243805
The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) promotes the splicing of group I introns by helping the intron RNA fold into the catalytically active structure. The regions required for...
8.
Eskes R, Liu L, Ma H, Chao M, Dickson L, Lambowitz A, et al.
Mol Cell Biol
. 2000 Oct;
20(22):8432-46.
PMID: 11046140
The yeast mitochondrial DNA group II introns aI1 and aI2 are retroelements that insert site specifically into intronless alleles by a process called homing. Here, we used patterns of flanking...
9.
Mohr S, Wanner L, Bertrand H, Lambowitz A
Nucleic Acids Res
. 2000 Sep;
28(13):1514-24.
PMID: 11001704
We characterized an unusual tRNA-like sequence that had been found inserted in suppressive variants of the mitochondrial retroplasmid of Neurospora intermedia strain Varkud. We previously identified two forms of the...
10.
Chen X, Gutell R, Lambowitz A
J Mol Biol
. 2000 Aug;
301(2):265-83.
PMID: 10926509
We used an Escherichia coli genetic assay based on the phage T4 td intron to test the ability of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) to suppress mutations...