A Krust
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Explore the profile of A Krust including associated specialties, affiliations and a list of published articles.
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54
Citations
4121
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Recent Articles
1.
Borjesson A, Windahl S, Karimian E, Eriksson E, Lagerquist M, Engdahl C, et al.
Am J Physiol Endocrinol Metab
. 2012 Mar;
302(11):E1381-9.
PMID: 22414805
High estradiol levels in late puberty induce growth plate closure and thereby cessation of growth in humans. In mice, the growth plates do not fuse after sexual maturation, but old...
2.
Borjesson A, Windahl S, Lagerquist M, Engdahl C, Frenkel B, Moverare-Skrtic S, et al.
Proc Natl Acad Sci U S A
. 2011 Mar;
108(15):6288-93.
PMID: 21444817
The bone-sparing effect of estrogen is primarily mediated via estrogen receptor-α (ERα), which stimulates target gene transcription through two activation functions (AFs), AF-1 in the N-terminal and AF-2 in the...
3.
Watanabe H, Takahashi E, Kobayashi M, Goto M, Krust A, Chambon P, et al.
J Mol Endocrinol
. 2006 Feb;
36(1):81-9.
PMID: 16461929
Recent studies have revealed that hundreds of genes in the uterus are activated by estrogen. Their expression profiles differ over time and doses and it is not clear whether all...
4.
Okada A, Ohta Y, Brody S, Watanabe H, Krust A, Chambon P, et al.
J Mol Endocrinol
. 2004 Jun;
32(3):615-25.
PMID: 15171704
Estrogen regulates proliferation and differentiation of epithelial cells in the mammalian oviduct, but pathways for cell-specific differentiation are not well understood. In the epithelial cells of the developing rat oviduct,...
5.
Garmy-Susini B, Delmas E, Gourdy P, Zhou M, Bossard C, Bugler B, et al.
Circ Res
. 2004 Apr;
94(10):1301-9.
PMID: 15073041
Both 17beta-estradiol (E2) and fibroblast growth factor-2 (FGF2) stimulate angiogenesis and endothelial cell migration and proliferation. The first goal of this study was to explore the potential link between this...
6.
Darblade B, Pendaries C, Krust A, Dupont S, Rami J, Chambon P, et al.
Circ Res
. 2002 Mar;
90(4):413-9.
PMID: 11884370
Although estradiol (E(2)) has been recognized to exert several vasculoprotective effects in several species, its effects in mouse vasomotion are unknown, and consequently, so is the estrogen receptor subtype mediating...
7.
Pendaries C, Darblade B, Rochaix P, Krust A, Chambon P, Korach K, et al.
Proc Natl Acad Sci U S A
. 2002 Feb;
99(4):2205-10.
PMID: 11854517
Two isoforms of estrogen receptor (ER) have been described: ERalpha and ERbeta. The initial gene targeting of ERalpha, consisting in the introduction of a Neo cassette in exon 1 [alphaERKO,...
8.
Sims N, Dupont S, Krust A, Clement-Lacroix P, Minet D, Resche-Rigon M, et al.
Bone
. 2002 Jan;
30(1):18-25.
PMID: 11792560
To determine the contributions of estrogen receptor (ER)alpha and ERbeta in bone growth and remodeling in male and female mice, we generated and analyzed full knockouts for each receptor, and...
9.
Krezel W, Dupont S, Krust A, Chambon P, Chapman P
Proc Natl Acad Sci U S A
. 2001 Oct;
98(21):12278-82.
PMID: 11593044
Estrogens are powerful modulators of neuronal physiology and in humans may affect a broad range of functions, including reproductive, emotional, and cognitive behaviors. We studied the contribution of estrogen receptors...
10.
Brouchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal J
Circulation
. 2001 Feb;
103(3):423-8.
PMID: 11157695
Background: The atheroprotective effect of 17beta-estradiol (E(2)) has been suggested in women and clearly demonstrated in animals through both an effect on lipid metabolism and a direct effect on the...