A K Rishi
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Explore the profile of A K Rishi including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
1168
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Recent Articles
1.
Fontana J, Rishi A
Leukemia
. 2002 Apr;
16(4):463-72.
PMID: 11960323
Retinoids are important mediators of cellular growth and differentiation. Retinoids modulate the growth of both normal and malignant cells through their binding to retinoid nuclear receptors and their subsequent activation....
2.
Yu Y, Rishi A, Turner J, Liu D, Black E, Moshier J, et al.
Am J Physiol Cell Physiol
. 2001 Apr;
280(5):C1083-9.
PMID: 11287320
Although epidermal growth factor receptor (EGFR) plays a key role in regulating cell proliferation, differentiation, and transformation in many tissues, little is known about the factor(s) that may modulate its...
3.
Farhana L, Boyanapalli M, Tschang S, Sun R, Hsu C, Zhang Y, et al.
Cell Growth Differ
. 2000 Nov;
11(10):541-50.
PMID: 11063127
Signal transduction via modulation of phosphorylation after selective inhibition of protein phosphatase (PP) 1 and/or PP2A appears to play a role in okadaic acid (OA)-mediated effects. Treatment of several estrogen...
4.
Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis
Fontana J, Dawson M, Leid M, Rishi A, Zhang Y, Hsu C, et al.
Int J Cancer
. 2000 May;
86(4):474-9.
PMID: 10797258
The retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN, CD437) induces apoptosis in a variety of cell types, many of which are cancer cells that resist the antiproliferative and/or differentiating effects of retinoids. While...
5.
Zhang Y, Rishi A, Dawson M, Tschang R, Farhana L, Boyanapalli M, et al.
Cancer Res
. 2000 Apr;
60(7):2025-32.
PMID: 10766194
The addition of all-trans-retinoic acid has been found to mediate a G1 cell cycle phase arrest but not apoptosis in normal mammary epithelial cells. We have now found that addition...
6.
Yoo J, Wang X, Rishi A, Lessor T, Xia X, Gustafson T, et al.
Br J Cancer
. 2000 Feb;
82(3):683-90.
PMID: 10682683
The processes by which ErbB-3, an inactive tyrosine kinase, exerts its biological effects are poorly understood. Using the yeast two-hybrid system, we have isolated an ErbB-3 binding protein (Ebp1) that...
7.
Rishi A, Sun R, Gao Y, Hsu C, Gerald T, Sheikh M, et al.
Nucleic Acids Res
. 1999 Aug;
27(15):3111-9.
PMID: 10454607
The biologically active synthetic retinoid CD437 (6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene, AHPN) and different human breast carcinoma (HBC) cell lines were used to examine the possible mechanism(s) of gadd45 induction. Northern blot analysis of...
8.
Zhang Y, Huang Y, Rishi A, Sheikh M, Shroot B, Reichert U, et al.
Exp Cell Res
. 1999 Feb;
247(1):233-40.
PMID: 10047465
6-[3-(1-Adamantyl)]-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) is a novel retinoid which induces apoptosis in the retinoic acid-resistant HL-60R human leukemia cell line. CD437-mediated poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis of HL-60R cells...
9.
Doyle L, Yang W, Abruzzo L, Krogmann T, Gao Y, Rishi A, et al.
Proc Natl Acad Sci U S A
. 1998 Dec;
95(26):15665-70.
PMID: 9861027
MCF-7/AdrVp is a multidrug-resistant human breast cancer subline that displays an ATP-dependent reduction in the intracellular accumulation of anthracycline anticancer drugs in the absence of overexpression of known multidrug resistance...
10.
Fontana J, Sun R, Rishi A, Dawson M, Ordonez J, Zhang Y, et al.
Oncol Res
. 1998 Dec;
10(6):313-24.
PMID: 9848102
Overexpression of bcl-2 or bcl-XL has been found to inhibit the induction of apoptosis in malignant cells by a large number of agents including a wide variety of chemotherapeutic drugs....