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A Jonczyk

Explore the profile of A Jonczyk including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 30
Citations 681
Followers 0
Related Specialties
Biochemistry
Chemistry
Pharmacology
Top 10 Co-Authors
S L Goodman
P Raddatz
W Knoll
H Kessler
B Diefenbach
C J Schmitges
A Offenhausser
R Naumann
G Holzemann
M Kreiter
Published In
J Med Chem
Radiol Diagn (Berl)
Eur J Pharm Sci
Biosens Bioelectron
Hoppe Seylers Z Physiol Chem
Affiliations
Soon will be listed here.
Recent Articles
1.
Cilengitide--exceptional pseudopolymorphism of a cyclic pentapeptide
Saal C, Lange M, Kuehn C, Untenecker H, Jonczyk A, Petersen S, et al.
Eur J Pharm Sci . 2015 Feb; 71:1-11. PMID: 25681628
Cilengitide (Cil) represents a cyclic pentapeptide, cyclo-(Arg-Gly-Asp-D-Phe-N-MeVal). Existence of an anhydrate form (A1) and a tetrahydrate form Cil1(H2O)4 has been observed. Surprisingly the anhydrate form proved to be more stable...
2.
A cyclo peptide activates signaling events and promotes growth and the production of the bone matrix
Pallu S, Bareille R, Dard M, Kessler H, Jonczyk A, Vernizeau M, et al.
Peptides . 2004 Jan; 24(9):1349-57. PMID: 14706549
The interaction of bone cells and their underlying extracellular matrix impacts biological processes such as maintenance of tissue integrity. The biological recognition of the extracellular matrix by attached cells is...
3.
Fusion of small unilamellar vesicles onto laterally mixed self-assembled monolayers of thiolipopeptides
Baumgart T, Kreiter M, Lauer H, Naumann R, Jung G, Jonczyk A, et al.
J Colloid Interface Sci . 2003 Mar; 258(2):298-309. PMID: 12618100
Monolayers of the thiolipopeptide NH(2)-Cys-Ala-Ser-Ala-Ala-Ser-Ser-Ala-Pro-Ser-Ser-(Myr)Lys(Myr)-OH (III) were formed on gold surfaces by self-assembly, mixed with a lateral spacer of the same peptide composition, NH(2)-Cys-Ala-Ser-Ala-Ala-Ser-Ser-Ala-Pro-Ser-Ser-Lys-OH (I). Different mixing ratios were employed...
4.
Determination of hydrochlorothiazide, triamterene and propranolol hydrochloride by the spectrophotometric method and high-performance liquid chromatography (HPLC)
Jonczyk A, Nowakowska Z
Acta Pol Pharm . 2002 Mar; 58(5):339-44. PMID: 11876440
Spectrophotometric and chromatographic (HPLC) methods for determination of hydrochlorothiazide, triamterene and propranolol hydrochloride were elaborated. Both methods were appropriate for the determination of three compounds in pharmaceutical preparations containing their...
5.
Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
Buerkle M, Pahernik S, Sutter A, Jonczyk A, Messmer K, Dellian M
Br J Cancer . 2002 Mar; 86(5):788-95. PMID: 11875744
Anti-angiogenetic cancer therapy is a potential new form for treatment of solid tumours. The alpha(v)-integrins (alpha(v)beta3, alpha(v)beta5) mediate the contact of activated endothelial cells to proteins of the extracellular matrix...
6.
Surface coating with cyclic RGD peptides stimulates osteoblast adhesion and proliferation as well as bone formation
Kantlehner M, Schaffner P, Finsinger D, Meyer J, Jonczyk A, Diefenbach B, et al.
Chembiochem . 2002 Feb; 1(2):107-14. PMID: 11828404
The physiological inertness of synthetic implant materials often results in insufficient implant integration and limited acceptance of implants in tissues. After implantation the implant surface is often separated from the...
7.
Function of linear and cyclic RGD-containing peptides in osteoprogenitor cells adhesion process
Verrier S, Pallu S, Bareille R, Jonczyk A, Meyer J, Dard M, et al.
Biomaterials . 2002 Jan; 23(2):585-96. PMID: 11761179
Cell adhesion directly influences cell growth, differentiation and migration as well as morphogenesis, integrity and repair. The extracellular matrix (ECM) elaborated by osteoblast cells constitutes a regulator of the cell...
8.
Proton transport through a peptide-tethered bilayer lipid membrane by the H(+)-ATP synthase from chloroplasts measured by impedance spectroscopy
Naumann R, Baumgart T, Graber P, Jonczyk A, Offenhausser A, Knoll W
Biosens Bioelectron . 2001 Dec; 17(1-2):25-34. PMID: 11742732
A lipid membrane was tethered to a gold film by a peptide spacer molecule terminated by a sulfhydryl group. Membranes were formed by fusion of liposomes prepared from egg phosphatidylcholine...
9.
RGD peptides and monoclonal antibodies, antagonists of alpha(v)-integrin, enter the cells by independent endocytic pathways
Castel S, Pagan R, Mitjans F, Piulats J, Goodman S, Jonczyk A, et al.
Lab Invest . 2001 Dec; 81(12):1615-26. PMID: 11742032
Cyclic synthetic peptides containing the arginine-glycine-aspartate motif (cRGD) and monoclonal antibodies (mAbs) targeted for individual integrins have been developed as potential therapeutic drugs for the treatment of several diseases. We...
10.
In vivo therapy of malignant melanoma by means of antagonists of alphav integrins
Mitjans F, Meyer T, Fittschen C, Goodman S, Jonczyk A, Marshall J, et al.
Int J Cancer . 2000 Aug; 87(5):716-23. PMID: 10925366
Integrin alphavbeta3 (vitronectin receptor) has been implicated in human malignant melanoma progression and angiogenesis as a receptor that provides survival signals. However, little is known about the therapeutic potential of...