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A Jagerschmidt

Explore the profile of A Jagerschmidt including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 20
Followers 0
Related Specialties
Pharmacology
Molecular Biology
Biochemistry
Top 10 Co-Authors
B P Roques
B Maigret
N Goudreau
N Guillaume
T Popovici
V Fleury
M Agnel
F Noble
M Anger-Leroy
D P OBrien
Published In
Mol Pharmacol
Biochem J
J Neurochem
Eur J Pharmacol
Affiliations
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Recent Articles
1.
Human thrombopoietin structure-function relationships: identification of functionally important residues
Jagerschmidt A, Fleury V, Anger-Leroy M, Thomas C, Agnel M, OBrien D
Biochem J . 1998 Jul; 333 ( Pt 3):729-34. PMID: 9677334
Thrombopoietin (TPO) is a haematopoietic growth factor responsible for megakaryocyte progenitor proliferation and differentiation. It belongs to the four-helix-bundle cytokine family and exerts its biological effects through binding to a...
2.
Binding sites and transduction process of the cholecystokininB receptor: involvement of highly conserved aromatic residues of the transmembrane domains evidenced by site-directed mutagenesis
Jagerschmidt A, Guillaume N, Roques B, Noble F
Mol Pharmacol . 1998 Jun; 53(5):878-85. PMID: 9584214
The functional significance of the extracellular amino-terminal region and of three highly conserved aromatic residues present in the fifth (TM-V) and sixth (TM-VI) transmembrane domains of the rat cholecystokinin (CCK)B...
3.
His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity
Jagerschmidt A, Vikland M, Goudreau N, Maigret B, Roques B
Eur J Pharmacol . 1996 Jan; 296(1):97-106. PMID: 8720482
A great interest is devoted to antagonists of the cholecystokinin type B (CCKB) receptor such as L-365,260, which reduces panic attacks in humans and to antagonists of the cholecystokinin type...
4.
Mutation of Asp100 in the second transmembrane domain of the cholecystokinin B receptor increases antagonist binding and reduces signal transduction
Jagerschmidt A, Guillaume N, Goudreau N, Maigret B, Roques B
Mol Pharmacol . 1995 Nov; 48(5):783-9. PMID: 7476907
We examined the functional significance of two residues present in the second (Asp100) and seventh (Asn391) transmembrane domains of the rat cholecystokininB (CCKB) receptor that are highly conserved among the...
5.
Identification and characterization of various cholecystokinin B receptor mRNA forms in rat brain tissue and partial determination of the cholecystokinin B receptor gene structure
Jagerschmidt A, Popovici T, ODonohue M, Roques B
J Neurochem . 1994 Oct; 63(4):1199-206. PMID: 7931273
Using the powerful method of DNA amplification, we have been able to isolate several cholecystokinin B (CCKB) receptor (CCKB-R) mRNA forms from rat brain tissue, allowing the detection of a...