A J Sant
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Explore the profile of A J Sant including associated specialties, affiliations and a list of published articles.
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40
Citations
488
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Recent Articles
1.
Nieto-Vesperinas M, Sanchez-Gil J, Sant A, Dainty J
Opt Lett
. 2009 Sep;
15(22):1261-3.
PMID: 19771059
We report numerical and experimental observations of a new transmission effect in rough dielectric interfaces.
2.
Sant A, Dainty J, Kim M
Opt Lett
. 2009 Sep;
14(21):1183-5.
PMID: 19759628
A method of replicating randomly rough surfaces fabricated in photoresist has been developed, enabling comparisons of the scattered light to be made between identical diffusers made from different materials. Experimental...
3.
Arneson L, KATZ J, Liu M, Sant A
J Immunol
. 2001 Dec;
167(12):6939-46.
PMID: 11739513
MHC class II molecules associate with peptides through pocket interactions and the formation of hydrogen bonds. The current paradigm suggests that the interaction of side chains of the peptide with...
4.
McFarland B, KATZ J, Beeson C, Sant A
Proc Natl Acad Sci U S A
. 2001 Jul;
98(16):9231-6.
PMID: 11470892
Comparison of crystallized MHC class II*peptide complexes has revealed that, in addition to pocket interactions involving the peptide side chains, peptide binding to MHC class II molecules is characterized by...
5.
Nanda N, Sant A
J Exp Med
. 2000 Sep;
192(6):781-8.
PMID: 10993909
The ability of the immune system to focus T cell responses against a select number of potential epitopes of a complex antigen is termed immunodominance. Epitopes that trigger potent T...
6.
Arneson L, Peterson M, Sant A
J Immunol
. 2000 Aug;
165(4):2059-67.
PMID: 10925290
Insulin-dependent diabetes mellitus is an autoimmune disease that is genetically linked to the HLA class II molecule DQ in humans and to MHC I-Ag7 in nonobese diabetic mice. The I-Ag7...
7.
Sant A, Beeson C, McFarland B, Cao J, Ceman S, Bryant P, et al.
Immunol Rev
. 2000 Jan;
172:239-53.
PMID: 10631950
Determination of the crystal structure of class II: peptide complexes has shown that in addition to pocket interactions involving the side chains of the peptide, peptide binding to MHC class...
8.
McFarland B, Sant A, Lybrand T, Beeson C
Biochemistry
. 1999 Dec;
38(50):16663-70.
PMID: 10600129
Proteins of the class II major histocompatibility complex (MHC) bind antigenic peptides that are subsequently presented to T cells. Previous studies have shown that most of the residues required for...
9.
Bryant P, Roos P, Ploegh H, Sant A
Eur J Immunol
. 1999 Oct;
29(9):2729-39.
PMID: 10508247
I-Ad molecules harboring single amino acid changes in the conserved 80-82 region of the beta-chain show altered trafficking in invariant chain (Ii)-negative cell lines. Since residues beta81 and beta82 form...
10.
McFarland B, Beeson C, Sant A
J Immunol
. 1999 Sep;
163(7):3567-71.
PMID: 10490947
The binding of peptides to MHC class II molecules is mediated in part by a conserved array of intermolecular hydrogen bonds. We have evaluated the consequences of disrupting the hydrogen...