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A J Dwork

Explore the profile of A J Dwork including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1005
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Recent Articles
1.
Pantazatos S, Huang Y, Rosoklija G, Dwork A, Arango V, Mann J
Mol Psychiatry . 2016 Aug; 22(5):760-773. PMID: 27528462
Brain gene expression profiling studies of suicide and depression using oligonucleotide microarrays have often failed to distinguish these two phenotypes. Moreover, next generation sequencing approaches are more accurate in quantifying...
2.
Rosoklija G, Duma A, Dwork A
Pril (Makedon Akad Nauk Umet Odd Med Nauki) . 2013 Aug; 34(1):95-8. PMID: 23917747
Macedonia is a small country, and the current state has been independent for only 22 years. Medical research, which requires an extensive infrastructure, has been limited. We describe our experience...
3.
Dwork A, Christensen J, Larsen K, Scalia J, Underwood M, Arango V, et al.
Neuroscience . 2009 Sep; 164(4):1557-64. PMID: 19782728
Anatomical evidence of brain damage from electroconvulsive therapy (ECT) is lacking; but there are no modern stereological studies in primates documenting its safety. Magnetic seizure therapy (MST) is under development...
4.
Haghighi F, Bach-Mizrachi H, Huang Y, Arango V, Shi S, Dwork A, et al.
Mol Psychiatry . 2008 Jan; 13(8):813-20. PMID: 18180764
Impaired brain serotonin neurotransmission is a potential component of the diathesis of major depression. Tryptophan hydroxylase-2 (TPH2), is the rate limiting biosynthetic isoenzyme for serotonin that is preferentially expressed in...
5.
Flynn S, Lang D, MacKay A, Goghari V, Vavasour I, Whittall K, et al.
Mol Psychiatry . 2003 Aug; 8(9):811-20. PMID: 12931208
Schizophrenia unfolds during the late period of brain maturation, while myelination is still continuing. In the present study, we used MRI and T2 relaxation analysis to measure the myelin water...
6.
Sawada K, Young C, Barr A, Longworth K, Takahashi S, Arango V, et al.
Mol Psychiatry . 2002 Jun; 7(5):484-92. PMID: 12082566
Recent imaging and postmortem studies suggest that impaired connectivity is involved in the pathophysiology of schizophrenia and major affective disorders. We investigated the presynaptic proteins complexin (Cx) I and Cx...
7.
Elgin V, Connolly E, Millar W, Feldstein N, Dwork A
Pediatr Dev Pathol . 2001 May; 4(3):289-97. PMID: 11370267
We present the first report of extramedullary hematopoiesis (EMH) in an encephalocele. The patient was a new-born with semilobar holoprosencephaly, a frontoethmoidal encephalocele, and a large subdural hematoma. The encephalocele...
8.
Mann J, Huang Y, Underwood M, Kassir S, OPPENHEIM S, Kelly T, et al.
Arch Gen Psychiatry . 2000 Aug; 57(8):729-38. PMID: 10920459
Background: Major depression and suicide are associated with fewer serotonin transporter (5-HTT) sites. The 5'-flanking promoter region of the 5-HTT gene has a biallelic insertion/deletion (5-HTTLPR). We assayed prefrontal cortical...
9.
Rosoklija G, Toomayan G, Ellis S, Keilp J, Mann J, Latov N, et al.
Arch Gen Psychiatry . 2000 Apr; 57(4):349-56. PMID: 10768696
Background: Postmortem studies of the subiculum from subjects with schizophrenia have detected smaller pyramidal cell bodies and diminished immunoreactivity for the dendritic protein, microtubule-associated protein 2. While these findings suggest...
10.
Rosoklija G, Dwork A, Younger D, Karlikaya G, Latov N, Hays A
Acta Neuropathol . 2000 Jan; 99(1):55-62. PMID: 10651028
Quantitative immunocytochemical analysis of complement proteins (CP) was performed on sural nerve biopsies from 15 patients with diabetic neuropathy (DN) and 18 nondiabetic patients with other forms of chronic neuropathy...