A J Docherty
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Explore the profile of A J Docherty including associated specialties, affiliations and a list of published articles.
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61
Citations
2336
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Recent Articles
1.
Davoli M, Lamplugh L, Beauchemin A, Chan K, Mordier S, Mort J, et al.
Dev Dyn
. 2001 Aug;
222(1):71-88.
PMID: 11507770
In the transformation of the cartilaginous epiphysis into bone, the first indication of change in the surfaces destined for resorption is the cleavage of aggrecan core protein by unidentified matrix...
2.
The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificity and inhibitor selectivity
Knauper V, Patterson M, Gomis-Ruth F, Smith B, Lyons A, Docherty A, et al.
Eur J Biochem
. 2001 Mar;
268(6):1888-96.
PMID: 11248710
Interstitial collagen is degraded by members of the matrix metalloproteinase (MMP) family, including MMP-1. Previous work has shown that the region of MMP-1 coded for by exon 5 is implicated...
3.
Nath D, Slocombe P, Webster A, Stephens P, Docherty A, Murphy G
J Cell Sci
. 2000 May;
113 ( Pt 12):2319-28.
PMID: 10825303
The ADAMs (A Disintegrin and Metalloprotease Domains) are a family of membrane-anchored proteins that play a role in fertilisation, myoblast fusion and ectodomain shedding of cell surface proteins. Meltrin gamma...
4.
Amour A, Knight C, Webster A, Slocombe P, Stephens P, Knauper V, et al.
FEBS Lett
. 2000 May;
473(3):275-9.
PMID: 10818225
A recombinant soluble form of the catalytic domain of human ADAM-10 was expressed as an Fc fusion protein from myeloma cells. The ADAM-10 was catalytically active, cleaving myelin basic protein...
5.
Kerkvliet E, Docherty A, Beertsen W, Everts V
Matrix Biol
. 1999 Oct;
18(4):373-80.
PMID: 10517184
Recent data suggest that gelatinase A (matrix metalloproteinase-2, MMP-2) plays an important role in the degradation of collagen of soft connective tissues. In an attempt to investigate its participation in...
6.
Amour A, Hutton M, Knauper V, Slocombe P, Webster A, Butler M, et al.
Ann N Y Acad Sci
. 1999 Jul;
878:728-31.
PMID: 10415820
No abstract available.
7.
Everts V, Korper W, Docherty A, Beertsen W
Ann N Y Acad Sci
. 1999 Jul;
878:603-6.
PMID: 10415785
No abstract available.
8.
Lee E, Murphy G, El-Alfy M, Davoli M, Lamplugh L, Docherty A, et al.
Dev Dyn
. 1999 Jul;
215(3):190-205.
PMID: 10398530
In order to determine which proteinases mediate the resorption of endochondral cartilage in the course of long bone development, a novel assay called "histozymography" has been developed. In this assay,...
9.
Everts V, Korper W, Jansen D, Steinfort J, Lammerse I, Heera S, et al.
FASEB J
. 1999 Jul;
13(10):1219-30.
PMID: 10385612
Data in the literature suggest that site-specific differences exist in the skeleton with respect to digestion of bone by osteoclasts. Therefore, we investigated whether bone resorption by calvarial osteoclasts (intramembranous...
10.
Zucker S, Mian N, Drews M, Conner C, Davidson A, Miller F, et al.
J Rheumatol
. 1999 Jan;
26(1):78-80.
PMID: 9918244
Objective: In view of evidence that stromelysin-1 and collagenase-1 are involved in tissue injury in inflammatory joint diseases, we sought to determine whether matrix metalloproteinases (MMP) are implicated in the...