A J Caton
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Explore the profile of A J Caton including associated specialties, affiliations and a list of published articles.
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44
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Recent Articles
1.
Kim J, Lee 4th M, Moore D, Sonawane S, Duff P, OConnor M, et al.
Am J Transplant
. 2009 Oct;
9(12):2736-44.
PMID: 19845585
Innate immune signals foster adaptive immunity through activation of antigen-presenting cells. Recent in vitro evidence suggests that innate signaling may also contribute to immunity by countering the effects of regulatory...
2.
Cozzo C, Lerman M, Boesteanu A, Larkin 3rd J, Jordan M, Caton A
Curr Top Microbiol Immunol
. 2005 Jun;
293:3-23.
PMID: 15981473
Regulatory T cells have been shown to prevent the development of autoimmune disease, and can modulate immune responses during infections or following tissue transplantation. Recently, the processes by which CD4+CD25+...
3.
Bensinger S, Bandeira A, Jordan M, Caton A, Laufer T
J Exp Med
. 2001 Aug;
194(4):427-38.
PMID: 11514600
CD4(+)25(+) T cells are a unique population of immunoregulatory T cells which are critical for the prevention of autoimmunity. To address the thymic selection of these cells we have used...
4.
Jordan M, Boesteanu A, Reed A, Petrone A, Holenbeck A, Lerman M, et al.
Nat Immunol
. 2001 Mar;
2(4):301-6.
PMID: 11276200
Despite accumulating evidence that regulatory T cells play a crucial role in preventing autoimmunity, the processes underlying their generation during immune repertoire formation are unknown. We show here that interactions...
5.
Riley M, Shih F, Jordan M, Petrone A, Cerasoli D, Scott P, et al.
Eur J Immunol
. 2001 Mar;
31(1):311-9.
PMID: 11265648
We have examined factors governing the differentiation of autoreactive CD4+ T cells that have evaded deletion by a self peptide. Two lineages of transgenic mice (HA12 and HA104) expressing the...
6.
Reed A, Riley M, Caton A
J Exp Med
. 2000 Dec;
192(12):1763-74.
PMID: 11120773
We have examined B cell populations that participate in distinct phases of the immune response to the influenza virus A/PR/8/34 hemagglutinin (HA) for their susceptibility to negative selection in mice...
7.
Riley M, Cerasoli D, Jordan M, Petrone A, Shih F, Caton A
J Immunol
. 2000 Oct;
165(9):4870-6.
PMID: 11046011
We have examined factors governing the negative selection of autoreactive CD4(+) T cells in transgenic mice expressing low (HA12 mice) vs. high (HA104 mice) amounts of the influenza virus hemagglutinin...
8.
Mandik-Nayak L, Nayak S, SOKOL C, Eaton-Bassiri A, Madaio M, Caton A, et al.
Int Immunol
. 2000 Mar;
12(3):353-64.
PMID: 10700470
bcl-2 transgenic mice develop anti-double-stranded (ds) DNA antibodies similar to those present in systemic lupus erythematosus. To begin to understand where a breakdown in the regulation of autoreactive lymphocytes is...
9.
Jordan M, Riley M, von Boehmer H, Caton A
Eur J Immunol
. 1999 Dec;
30(1):136-44.
PMID: 10602035
To examine the role of cognate peptide in establishing CD4(+) T cell tolerance, we have mated transgenic mice that express the major I-E(d)-restricted determinant (S1) from the influenza virus PR8...
10.
Caton A, Cerasoli D, Shih F
Immunol Res
. 1998 Feb;
17(1-2):23-32.
PMID: 9479564
To analyze mechanisms governing tolerance and autoimmunity to self-antigens, we have generated lineages of transgenic mice that express the influenza virus PR8 hemagglutinin (HA) as a neo-self-antigen. By comparing the...