A Ivan Hernandez
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Explore the profile of A Ivan Hernandez including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
394
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Recent Articles
1.
Hou J, Allen K, Hernandez A, Cottrell J, Kass I
NeuroSci
. 2025 Feb;
6(1).
PMID: 39982261
Hypoxia due to stroke is a major cause of neuronal damage, leading to loss of cognition and other brain functions. Sevoflurane preconditioning improves recovery after hypoxia. Hypoxia interferes with protein...
2.
Tsokas P, Hsieh C, Flores-Obando R, Bernabo M, Tcherepanov A, Hernandez A, et al.
Sci Adv
. 2024 Jun;
10(26):eadl0030.
PMID: 38924398
How can short-lived molecules selectively maintain the potentiation of activated synapses to sustain long-term memory? Here, we find kidney and brain expressed adaptor protein (KIBRA), a postsynaptic scaffolding protein genetically...
3.
Vingan I, Phatarpekar S, Tung V, Hernandez A, Evgrafov O, Alarcon J
bioRxiv
. 2024 Jan;
PMID: 38260257
The rodent hippocampus is a spatially organized neuronal network that supports the formation of spatial and episodic memories. We conducted bulk RNA sequencing and spatial transcriptomics experiments to measure gene...
4.
Baena-Caldas G, Li J, Pedraza L, Ghosh S, Kalmes A, Barone F, et al.
PLoS One
. 2024 Jan;
19(1):e0295504.
PMID: 38166102
Background: Stroke is a major cause of death, disability, and public health problems. Its intervention is limited to early treatment with thrombolytics and/or endovascular clot removal with mechanical thrombectomy without...
5.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, et al.
Commun Biol
. 2022 Oct;
5(1):1074.
PMID: 36209301
Dysregulation of sphingomyelin and ceramide metabolism have been implicated in Alzheimer's disease. Genome-wide and transcriptome-wide association studies have identified various genes and genetic variants in lipid metabolism that are associated...
6.
Flores-Obando R, Freidin M, Hernandez A, Abrams C
Mol Cell Neurosci
. 2022 Mar;
120:103716.
PMID: 35276347
Pelizaeus-Merzbacher-like disease type 1 (PMLD1) is a hypomyelinating disorder arising in patients with mutations in GJC2, encoding Connexin47 (Cx47). PMLD1 causes nystagmus, cerebellar ataxia, spasticity and changes in CNS white...
7.
Hsieh C, Tsokas P, Grau-Perales A, Lesburgueres E, Bukai J, Khanna K, et al.
Eur J Neurosci
. 2021 Feb;
54(8):6795-6814.
PMID: 33540466
PKMζ is an autonomously active PKC isoform crucial for the maintenance of synaptic long-term potentiation (LTP) and long-term memory. Unlike other kinases that are transiently stimulated by second messengers, PKMζ...
8.
Laing K, Simoes S, Baena-Caldas G, Lao P, Kothiya M, Igwe K, et al.
Brain Commun
. 2020 Nov;
2(2):fcaa132.
PMID: 33215083
Small vessel cerebrovascular disease, visualized as white matter hyperintensities on T2-weighted magnetic resonance imaging, contributes to the clinical presentation of Alzheimer's disease. However, the extent to which cerebrovascular disease represents...
9.
Regier M, Liang J, Choi A, Verma K, Libien J, Hernandez A
Neural Plast
. 2019 Dec;
2019:4383258.
PMID: 31827497
Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear protein that regulates gene expression through poly(ADP)-ribosylation, resulting in the loosening of chromatin structure. PARP-1 enzymatic activity has been shown to be necessary for...
10.
Allen K, Regier M, Hsieh C, Tsokas P, Barnard M, Phatarpekar S, et al.
PLoS One
. 2018 Oct;
13(10):e0203374.
PMID: 30281601
The transition from short-term to long-term forms of synaptic plasticity requires protein synthesis and new gene expression. Most efforts to understand experience-induced changes in neuronal gene expression have focused on...