A Helen Taylor
Overview
Explore the profile of A Helen Taylor including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
279
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Recent Articles
1.
Jackson M, Fidanza A, Taylor A, Rybtsov S, Axton R, Kydonaki M, et al.
Stem Cell Reports
. 2021 Mar;
16(4):727-740.
PMID: 33667414
Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance...
2.
Fidanza A, Stumpf P, Ramachandran P, Tamagno S, Babtie A, Lopez-Yrigoyen M, et al.
Blood
. 2020 Jul;
136(25):2893-2904.
PMID: 32614947
Hematopoietic stem and progenitor cells (HSPCs) develop in distinct waves at various anatomical sites during embryonic development. The in vitro differentiation of human pluripotent stem cells (hPSCs) recapitulates some of...
3.
Lopez-Yrigoyen M, Yang C, Fidanza A, Cassetta L, Taylor A, McCahill A, et al.
Nat Commun
. 2019 Feb;
10(1):881.
PMID: 30787325
Red blood cells mature within the erythroblastic island (EI) niche that consists of specialized macrophages surrounded by differentiating erythroblasts. Here we establish an in vitro system to model the human...
4.
Lopez-Yrigoyen M, Fidanza A, Cassetta L, Axton R, Taylor A, Meseguer-Ripolles J, et al.
Philos Trans R Soc Lond B Biol Sci
. 2018 May;
373(1750).
PMID: 29786554
We describe the production of a human induced pluripotent stem cell (iPSC) line, SFCi55-ZsGr, that has been engineered to express the fluorescent reporter gene, ZsGreen, in a constitutive manner. The...
5.
Haideri S, McKinnon A, Taylor A, Kirkwood P, Starkey Lewis P, ODuibhir E, et al.
NPJ Regen Med
. 2018 Jan;
2:31.
PMID: 29303159
[This corrects the article DOI: 10.1038/s41536-017-0017-0.].
6.
Haideri S, McKinnon A, Taylor A, Kirkwood P, Starkey Lewis P, ODuibhir E, et al.
NPJ Regen Med
. 2018 Jan;
2:14.
PMID: 29302350
Chronic liver injury can be caused by viral hepatitis, alcohol, obesity, and metabolic disorders resulting in fibrosis, hepatic scarring, and cirrhosis. Novel therapies are urgently required and previous work has...
7.
Fidanza A, Lopez-Yrigoyen M, Romano N, Jones R, Taylor A, Forrester L
Sci Rep
. 2017 Jul;
7(1):6394.
PMID: 28743878
We have generated a drug-free, all-in-one dCAS9-SAM vector that can activate endogenous gene expression with the potential to modify cell fate. We demonstrate that this strategy can be used in...
8.
Yang C, Ma R, Axton R, Jackson M, Taylor A, Fidanza A, et al.
Stem Cells
. 2016 Dec;
35(4):886-897.
PMID: 28026072
Blood transfusion is widely used in the clinic but the source of red blood cells (RBCs) is dependent on donors, procedures are susceptible to transfusion-transmitted infections and complications can arise...
9.
Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al.
Stem Cells Transl Med
. 2016 Jun;
5(8):981-90.
PMID: 27352929
Unlabelled: : We have developed a robust, Good Manufacturing Practice-compatible differentiation protocol capable of producing scalable quantities of red blood cells (RBCs) from human pluripotent stem cells (hPSCs). However, translation...
10.
Kara M, Axton R, Jackson M, Ghaffari S, Buerger K, Watt A, et al.
Stem Cells
. 2015 Jul;
33(10):3077-86.
PMID: 26175344
Mesenchymal stem cells (MSCs) isolated from many tissues including bone marrow and fat can be expanded in vitro and can differentiate into a range of different cell types such as...