A H Zea
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Explore the profile of A H Zea including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
252
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Recent Articles
1.
Matossian M, Chang T, Wright M, Burks H, Elliott S, Sabol R, et al.
Clin Transl Oncol
. 2021 Aug;
24(1):127-144.
PMID: 34370182
Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs)...
2.
Taheri F, Ochoa J, Faghiri Z, Culotta K, Park H, Lan M, et al.
Clin Cancer Res
. 2001 Apr;
7(3 Suppl):958s-965s.
PMID: 11300497
L-Arginine is a versatile amino acid that plays a central role in the normal function of several organ systems including the immune system. Its availability is tightly controlled and varies...
3.
Bosco M, Curiel R, Zea A, Malabarba M, Ortaldo J, Espinoza-Delgado I
J Immunol
. 2000 Apr;
164(9):4575-85.
PMID: 10779760
The activating properties of IL-2 and the structure of the IL-2R on human monocytes are well characterized. However, relatively little is known about the biochemical mechanisms involved in IL-2 signal...
4.
Gratama J, Zea A, Bolhuis R, Ochoa A
Cancer Immunol Immunother
. 1999 Sep;
48(5):263-9.
PMID: 10478643
A decrease in lymphocyte signal-transduction molecules, described in cancer patients and patients with chronic infectious diseases, has been proposed as a possible mechanism leading to an impaired immune response in...
5.
Horiguchi S, Petersson M, Nakazawa T, Kanda M, Zea A, Ochoa A, et al.
Cancer Res
. 1999 Jun;
59(12):2950-6.
PMID: 10383160
Whereas transplantable tumors can be readily cured with immunotherapeutic approaches, similar therapies in cancer patients have been less effective. This difference may be explained by an immunosuppression resulting from the...
6.
Zea A, Ochoa M, Ghosh P, Longo D, Alvord W, Valderrama L, et al.
Infect Immun
. 1998 Feb;
66(2):499-504.
PMID: 9453602
Advanced stages of mycobacterial diseases such as leprosy and tuberculosis are characterized by a loss of T-cell function. The basis of this T-cell dysfunction is not well understood. The present...
7.
Fenton R, Steis R, Madara K, Zea A, Ochoa A, Janik J, et al.
J Immunother Emphasis Tumor Immunol
. 1996 Sep;
19(5):364-74.
PMID: 8941876
We performed a prospective, randomized study to determine whether subcutaneous administration of interleukin-2 (IL-2) in combination with an autologous renal cell vaccine is feasible and can potentiate antitumor immunity. Seventeen...
8.
Zea A, Curti B, Longo D, Alvord W, Strobl S, Mizoguchi H, et al.
Clin Cancer Res
. 1995 Nov;
1(11):1327-35.
PMID: 9815928
We have recently described molecular changes in T cells from tumor-bearing patients that are associated with depressed immune function. The present work investigates changes in T-cell signal transduction proteins including...
9.
Franco J, Ghosh P, Wiltrout R, Carter C, Zea A, Momozaki N, et al.
Cancer Res
. 1995 Sep;
55(17):3840-6.
PMID: 7641202
Flavone-8-acetic acid plus recombinant human interleukin 2 is a successful antitumor therapy in mice bearing the Renca murine renal cell carcinoma. This report demonstrates that T cells, particularly CD8+ T...
10.
Bosco M, Pulkki K, Rowe T, Zea A, Musso T, Longo D, et al.
J Immunol
. 1995 Aug;
155(3):1411-9.
PMID: 7636206
Human monocytes express functional IL-2 receptors (IL-2R) and are directly activated by IL-2 to exert effector and secretory functions. In this study, we show that IL-4 selectively suppressed, in a...