A H Harken
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Explore the profile of A H Harken including associated specialties, affiliations and a list of published articles.
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298
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2276
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Recent Articles
1.
Raeburn C, Zimmerman M, Banerjee A, Cleveland Jr C, Harken A
Minerva Chir
. 2004 Jul;
59(3):209-18.
PMID: 15252386
In 1986, Murry et al. reported that brief periods of antecedent ischemia in dogs paradoxically reduced (rather than exacerbated) the size of myocardial infarcts created by subsequent prolonged ischemia. This...
2.
Zimmerman M, Selzman C, Raeburn C, Calkins C, Barsness K, Harken A
J Card Surg
. 2002 Apr;
16(6):490-7.
PMID: 11925031
Angiogenesis is fundamental to both normal physiologic (wound healing) and pathologic (cancer) processes. Manipulation of divergent angiogenic signals promises effective therapy of atherosclerotic cardiovascular disease. Positive proangiogenic strategies promise collateral...
3.
Differential cardiopulmonary recruitment of neutrophils during hemorrhagic shock: a role for ICAM-1?
Song Y, Ao L, Calkins C, Raeburn C, Harken A, Meng X
Shock
. 2002 Jan;
16(6):444-8.
PMID: 11770042
Hemorrhagic shock and subsequent resuscitation can result in acute lung injury and cardiac dysfunction. Previous studies have demonstrated that tissue neutrophil accumulation contributes to cardiopulmonary injury associated with trauma. Thus,...
4.
Raeburn C, Cleveland Jr J, Zimmerman M, Harken A
Arch Surg
. 2001 Dec;
136(11):1263-6.
PMID: 11695970
The initial discovery of cardiac preconditioning has evolved into an exciting series of practical surgical applications. An enormous amount of evidence demonstrating both the safety and efficacy of ischemic preconditioning...
5.
Meng X, Ao L, Shames B, Harken A
J Surg Res
. 2001 Dec;
101(2):210-5.
PMID: 11735278
Background: Local tumor necrosis factor (TNF)-alpha production by resident macrophages (M phi) contributes to posttraumatic tissue injury. Hypoxia decreases cellular cyclic adenosine monophosphate (cAMP) levels and enhances M phi secretion...
6.
Song Y, Ao L, Raeburn C, Calkins C, Abraham E, Harken A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2001 Aug;
281(3):L677-84.
PMID: 11504696
Acute lung injury after hemorrhagic shock (HS) is associated with the expression of tumor necrosis factor (TNF)-alpha in the lung. However, the role of TNF-alpha and its receptors in this...
7.
Raeburn C, Calkins C, Zimmerman M, Song Y, Ao L, Banerjee A, et al.
Surgery
. 2001 Aug;
130(2):319-25.
PMID: 11490366
Background: Sepsis-induced cardiac dysfunction occurs commonly in critically ill patients and is associated with high mortality rates. Neutrophils play a central role in sepsis-induced lung and liver injury; however, the...
8.
Meldrum K, Meldrum D, Hile K, Burnett A, Harken A
J Surg Res
. 2001 Jul;
99(2):288-93.
PMID: 11469899
Purpose: Renal ischemia-reperfusion (IR) injury is a devastating clinical problem. While effective animal models have been developed to investigate this condition, they are limited by differential renal cell inflammatory mediator...
9.
Shames B, McIntyre Jr R, Bensard D, Pulido E, Selzman C, Reznikov L, et al.
J Surg Res
. 2001 Jul;
99(2):187-93.
PMID: 11469886
Background: Elevation of cellular cAMP inhibits lipopolysaccharide(LPS)-stimulated tumor necrosis factor alpha (TNF-alpha) production and increases the expression of interleukin (IL)-10 in mononuclear cells. TNF-alpha gene expression obligates activation of the...
10.
Selzman C, Miller S, Harken A
Ann Thorac Surg
. 2001 Jun;
71(6):2066-74.
PMID: 11426810
Atherosclerosis represents a spectrum of pathologic lesions with diverse clinical sequelae. In this review, we build upon the paradigm that arteriosclerosis represents an inflammatory disease. By examining mechanisms involved in...