A Guerami
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Explore the profile of A Guerami including associated specialties, affiliations and a list of published articles.
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9
Citations
18
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Recent Articles
1.
Guerami A, GRIFFIN J, Kovacs W, Grino P, MACDONALD P, Wilson J
J Clin Endocrinol Metab
. 1990 Jul;
71(1):247-51.
PMID: 2370295
Defects of the androgen receptor in 46,XY individuals cause aberrant virilization that varies from a female phenotype to men with minor defects. More severely affected individuals also develop gynecomastia associated...
2.
Guerami A, Varner M, Shackleton C, MACDONALD P, CASEY M
J Steroid Biochem
. 1988 Jan;
29(1):57-62.
PMID: 3347051
The activity of steroid 21-sulfatase, the enzyme that catalyzes the hydrolysis of deoxycorticosterone sulfate (DOC-SO4) is demonstrable in human placenta. Thus, it is possible that this placental enzyme, by way...
3.
CASEY M, Winkel C, Guerami A, MACDONALD P
J Steroid Biochem
. 1987 Jan;
27(4-6):1013-5.
PMID: 3695502
During pregnancy, deoxycorticosterone (DOC) in maternal plasma is produced principally by 21-hydroxylation of circulating progesterone in a number of extra-adrenal tissues. Estrogen acts, directly or indirectly, to increase the transfer...
4.
Milewich L, MACDONALD P, Guerami A, Midgett W, Lassiter W, Carr B
J Clin Endocrinol Metab
. 1986 Jul;
63(1):180-91.
PMID: 3711258
The properties of human fetal liver (HFL) estrogen 16 alpha-hydroxylase (16 alpha-OHase) were studied in microsomal preparations and hepatocytes maintained in culture. A specific assay was developed for the determination...
5.
Berkovitz G, Guerami A, Brown T, MACDONALD P, Migeon C
J Clin Invest
. 1985 Jun;
75(6):1763-9.
PMID: 3924954
We evaluated a family in which gynecomastia occurred in five males in two generations. In each affected subject, gynecomastia and male sexual maturation began at an early age. The ratio...
6.
CASEY M, Guerami A, Milewich L, Gomez-Sanchez C, MACDONALD P
J Clin Invest
. 1985 Apr;
75(4):1335-8.
PMID: 3988939
It is known that 19-nor-deoxycorticosterone (19-nor-DOC) is a potent mineralocorticosteroid that is present in urine of rats and humans in a free, i.e., nonconjugated, form. In some forms of hypertension...
7.
Guerami A, MACDONALD P, CASEY M
J Clin Endocrinol Metab
. 1984 Jun;
58(6):1148-52.
PMID: 6725510
In the present investigation, we determined the transfer constant of conversion of plasma estrone to estriol (E3) ( [rho] E1- E3BU ) in men, postmenopausal women, and premenopausal parous and...
8.
CASEY M, Guerami A, Winkel C, MACDONALD P
J Steroid Biochem
. 1984 Jan;
20(1):237-43.
PMID: 6323863
DOC and DOC-SO4, which are present in large amounts in the blood of pregnant women, are derived from sources other than maternal adrenal. Other investigators demonstrated that treatment of near-term...
9.
Guerami A, CASEY M, MACDONALD P
J Steroid Biochem
. 1983 Aug;
19(2):1173-7.
PMID: 6887924
In the present investigation, we determined the metabolic clearance rate of plasma deoxycorticosterone sulfate in adult men and nonpregnant women and in one women pregnant at 42 weeks gestation with...