A Gahm
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Explore the profile of A Gahm including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
242
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Recent Articles
1.
Zhivotovsky B, Samali A, Gahm A, Orrenius S
Cell Death Differ
. 1999 Aug;
6(7):644-51.
PMID: 10453075
The activation of the caspase family of proteases has been detected in numerous cell systems and appears to function as a common pathway through which apoptotic mechanisms may operate. Caspases...
2.
Kohler C, Gahm A, Noma T, Nakazawa A, Orrenius S, Zhivotovsky B
FEBS Lett
. 1999 Apr;
447(1):10-2.
PMID: 10218571
The release of two mitochondrial proteins, cytochrome c and apoptosis-inducing factor (AIF), into the soluble cytoplasm of cells undergoing apoptosis is well established. Using spectrophotometric determination of enzyme activity, the...
3.
Zhivotovsky B, Gahm A, Orrenius S
Biochem Biophys Res Commun
. 1997 Apr;
233(1):96-101.
PMID: 9144403
To investigate the involvement of different proteases in the execution step of apoptosis and to determine their intracellular location, isolated rat thymocyte nuclei were incubated either in the presence of...
4.
Jiang S, Zhivotovsky B, Burgess D, Gahm A, Chow S, Orrenius S
Cell Death Differ
. 1997 Jan;
4(1):39-50.
PMID: 16465209
Our previous work showed that chelation of intracellular Zn2+ with N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine (TPEN) induces apoptosis in rat thymocytes. The molecular mechanism involved in TPEN-triggered apoptosis remains unknown, except that...
5.
Zhivotovsky B, Gahm A, Ankarcrona M, Nicotera P, Orrenius S
Exp Cell Res
. 1995 Dec;
221(2):404-12.
PMID: 7493640
To investigate the involvement of proteases in apoptosis, rat thymocytes were treated with the glucocorticoid hormone methylprednisolone or the topoisomerase II inhibitor etoposide in the presence of selective substrate inhibitors...
6.
Kass G, Chow S, Gahm A, Webb D, Berggren P, Llopis J, et al.
Biochim Biophys Acta
. 1994 Sep;
1223(2):226-33.
PMID: 8086492
The plasma membrane Ca2+ carrier system involved in receptor-mediated Ca2+ entry was studied. Using the Ca2+ readdition protocol, the rate of cytosolic free Ca2+ concentration ([Ca2+]i) increase in vasopressin-pretreated hepatocytes...
7.
Zhivotovsky B, Wade D, Gahm A, Orrenius S, Nicotera P
FEBS Lett
. 1994 Sep;
351(2):150-4.
PMID: 8082754
Isolated rat liver nuclei were incubated in the presence of divalent cations, and the mechanisms underlying the subsequent chromatin fragmentation were investigated. Either of the two cations, Ca2+ or Mg2+...
8.
Kass G, Gahm A, Llopis J
Cell Signal
. 1994 Jul;
6(5):493-501.
PMID: 7818985
The regulation of Ca2+ influx in rat hepatocytes by glucagon and cyclic AMP (cAMP) was investigated. Exposing hepatocytes to glucagon resulted in an increase in the initial rate of Ca2+...
9.
Llopis J, Farrell G, Duddy S, Kass G, Gahm A, Orrenius S
Biochem Pharmacol
. 1993 Jun;
45(11):2209-14.
PMID: 8390834
In the isolated perfused rat liver 2,5-di(tert-butyl)hydroquinone (tBuHQ), a selective inhibitor of the endoplasmic reticulum Ca2+ pump, induces a prolonged glucose output and stimulates Ca2+ efflux. The present study shows...
10.
Llopis J, Kass G, Gahm A, Orrenius S
Biochem J
. 1992 May;
284 ( Pt 1):243-7.
PMID: 1318023
Receptor-mediated Ca2+ entry was studied in fura-2-loaded isolated hepatocytes. Emptying of internal Ca2+ stores by treatment with either the Ca(2+)-mobilizing hormone vasopressin or the inhibitors of the microsomal Ca2+ pump,...