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A Craig Mackinnon

Explore the profile of A Craig Mackinnon including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 509
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Recent Articles
11.
Tsai S, Christians K, George B, Ritch P, Dua K, Khan A, et al.
Ann Surg . 2018 Aug; 268(4):610-619. PMID: 30080723
Objectives: One facet of precision medicine is the use of tumor molecular profiling to guide chemotherapeutic selection. We conducted the first prospective clinical trial of molecular profiling to guide neoadjuvant...
12.
Roy I, Boyle K, Vonderhaar E, Zimmerman N, Gorse E, Mackinnon A, et al.
Lab Invest . 2017 Jan; 97(3):302-317. PMID: 28092365
The mechanisms by which the extreme desmoplasia observed in pancreatic tumors develops remain unknown and its role in pancreatic cancer progression is unsettled. Chemokines have a key role in the...
13.
Robin A, Cohen E, Chongkrairatanakul T, Saad E, Mackinnon A
Ann Diagn Pathol . 2016 Jul; 23:32-4. PMID: 27402221
Renal cell carcinoma (RCC) in the allograft of kidney transplant recipient (KTR) patients is rare and may represent a de novo process arising from the transplanted organ or metastasis from...
14.
Bradley W, Eng K, Le M, Mackinnon A, Kendziorski C, Rader J
BMC Clin Pathol . 2015 Sep; 15:17. PMID: 26412982
Background: Previously, we have used clinical and gene expression data from The Cancer Genome Atlas (TCGA) to model a pathway-based index predicting outcomes in ovarian carcinoma. This data were obtained...
15.
Rao N, Mackinnon A, Routes J
Hum Pathol . 2015 Jul; 46(9):1306-14. PMID: 26138782
Common variable immunodeficiency is a primary immunodeficiency of unknown etiology characterized by low serum immunoglobulin G, a decreased ability to make specific antibodies, and variable T-cell defects. Approximately 10-30% of...
16.
Roy I, Zimmerman N, Mackinnon A, Tsai S, Evans D, Dwinell M
PLoS One . 2014 Mar; 9(3):e90400. PMID: 24594697
Pancreatic ductal adenocarcinoma is an unsolved health problem with nearly 75% of patients diagnosed with advanced disease and an overall 5-year survival rate near 5%. Despite the strong link between...
17.
Chase N, Verbsky J, Hintermeyer M, Waukau J, Tomita-Mitchell A, Casper J, et al.
J Clin Immunol . 2012 Aug; 33(1):30-9. PMID: 22930256
Purpose: A subset of patients with common variable immunodeficiency (CVID) develops granulomatous and lymphocytic interstitial lung disease (GLILD), a restrictive lung disease associated with early mortality. The optimal therapy for...
18.
Gordon I, Sitterding S, Mackinnon A, Husain A
Arch Pathol Lab Med . 2009 Aug; 133(7):1106-15. PMID: 19642737
Context: Lung cancer is a common disease frequently seen by the surgical pathologist. Although secondary to improvements in screening and radiologic techniques and aggressive resection of small pulmonary nodules, the...
19.
Gordon I, Cipriani N, Arif Q, Mackinnon A, Husain A
Arch Pathol Lab Med . 2009 Aug; 133(7):1096-105. PMID: 19642736
Context: Nonneoplastic lung diseases include a wide range of pathologic disorders from asthma to interstitial lung disease to pulmonary hypertension. Recent advances in our understanding of the pathophysiology of many...
20.
Mackinnon A, Yan B, Joseph L, Al-Ahmadie H
Arch Pathol Lab Med . 2009 Aug; 133(7):1033-40. PMID: 19642730
Context: Recent studies have uncovered a number of possible mechanisms by which prostate cancers can become resistant to systemic androgen deprivation, most involving androgen-independent reactivation of the androgen receptor. Genome-wide...