A Callaerts
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Explore the profile of A Callaerts including associated specialties, affiliations and a list of published articles.
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16
Citations
39
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Recent Articles
1.
Rogiers V, Vandenberghe Y, Callaerts A, Sonck W, Vercruysse A
Toxicol In Vitro
. 2010 Aug;
4(4-5):439-42.
PMID: 20702210
Addition of 2% dimethylsulphoxide (DMSO) to the medium has been described to retain biochemical and morphological differentiation of cultured rat hepatocytes. The maintenance of differentiated hepatocytes for a long time...
2.
Coecke S, Callaerts A, Phillips I, Vercruysse A, Shephard E, Rogiers V
Toxicol In Vitro
. 2010 Jul;
12(4):335-41.
PMID: 20654415
The regulation of flavin-containing monooxygenase (FMO) by thyroid hormones was examined under well defined in vitro conditions using adult male rat hepatocytes co-cultured with rat liver epithelial cells of primitive...
3.
De Smet K, Callaerts A, Vercruysse A, Rogiers V
Toxicol In Vitro
. 2010 Jul;
11(5):459-63.
PMID: 20654335
Ethoxycoumarin-O-deethylase (ECOD) and microsomal epoxide hydrase (mEH) activities have been studied in collagen gel cultures of rat hepatocytes under control conditions and after exposure to phénobarbital. The hepatocytes were either...
4.
De Sousa G, Nicolas F, Placidi M, Rahmani R, Benicourt M, Vannier B, et al.
Chem Biol Interact
. 1999 Jul;
121(1):77-97.
PMID: 10418972
Ethical, economic and technical reasons hinder regular supply of freshly isolated hepatocytes from higher mammals such as monkey for preclinical evaluation of drugs. Hence, we aimed at developing optimal and...
5.
Rogiers V, Vandenberghe Y, Vanhaecke T, Geerts A, Callaerts A, Carleer J, et al.
Arch Toxicol
. 1997 Jan;
71(5):271-82.
PMID: 9137805
Milacemide or 2-n-pentylaminoacetamide hydrochloride, a new glycine derivative, was found to cause elevations of plasma transaminases in patients suffering from severe depression and Alzheimer's disease. However, no signs of liver...
6.
Cornet M, Callaerts A, Jorritsma U, Bolt H, Vercruysse A, Rogiers V
Chem Res Toxicol
. 1995 Oct;
8(7):987-92.
PMID: 8555415
The biotransformation of 2-methylpropene, a gaseous alkene widely used in industry, was investigated in vitro in liver tissue of rats, mice, and humans. Interspecies comparison revealed that the lowest levels...
7.
Cornet M, Callaerts A, Vercruysse A, Rogiers V
Arch Toxicol
. 1995 Jan;
70(1):64-7.
PMID: 8750908
The epoxidation of the gaseous alkene 2-methylpropene or isobutene was studied in vitro in rat lung tissue in comparison with rat liver. Pulmonary tissue appears to be less exposed to...
8.
Cornet M, Mertens K, Callaerts A, Sonck W, Vercruysse A, Rogiers V
Mech Ageing Dev
. 1994 May;
74(1-2):103-15.
PMID: 7934201
The effect of age and gender on the in vitro biotransformation of 2-methylpropene, an alkene metabolized to 2-methyl-1,2-epoxypropane, was studied. The epoxide concentration and the epoxide metabolizing enzymatic activities were...
9.
Coecke S, Mertens K, Segaert A, Callaerts A, Vercruysse A, Rogiers V
Anal Biochem
. 1992 Sep;
205(2):285-8.
PMID: 1443574
The determination of the mixed function flavin-containing monooxygenase activity in rat liver and in hepatocytes and their cultures by spectrophotometric measurement of the oxygenation of methimazole is complicated by an...
10.
Rogiers V, Callaerts A, Vercruysse A, Akrawi M, Shephard E, Phillips I
Pharm Weekbl Sci
. 1992 Jun;
14(3A):127-31.
PMID: 1502013
Male Wistar rats were in vivo exposed for 2 weeks to 100 micrograms/ml sodium valproate by subcutaneous implantation of osmotic pumps and hepatocytes were isolated. As an in vitro model...