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A C Murphy

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Articles 13
Citations 177
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Recent Articles
1.
Bilocca D, Hargadon B, Pavord I, Green R, Brightling C, Bradding P, et al.
Chron Respir Dis . 2017 Jun; 15(1):85-87. PMID: 28569072
The use of oral methotrexate for refractory eosinophilic asthma in a tertiary asthma referral centre, Glenfield Hospital, Leicester, was evaluated between January 2006 and December 2014. The patients ( n...
2.
Goussous S, Casford M, Murphy A, Salmond G, Leeper F, Davies P
J Phys Chem B . 2017 Apr; 121(19):5072-5077. PMID: 28437109
The lipopeptide surfactin produced by certain strains of Bacillus subtilis is a powerful biosurfactant possessing potentially useful antimicrobial properties. In order to better understand its surface behavior, we have used...
3.
Murphy A, Weyhenmeyer B, Noonan J, Kilbride S, Schimansky S, Loh K, et al.
Apoptosis . 2013 Nov; 19(4):629-42. PMID: 24213561
Glioblastoma (GBM) is the most aggressive form of primary brain tumour, with dismal patient outcome. Treatment failure is associated with intrinsic or acquired apoptosis resistance and the presence of a...
4.
Murphy A, Weyhenmeyer B, Schmid J, Kilbride S, Rehm M, Huber H, et al.
Cell Death Dis . 2013 May; 4:e629. PMID: 23681224
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. GBM cells are highly resistant to apoptosis induced by antitumor drugs and radiotherapy resulting in cancer progression....
5.
Weyhenmeyer B, Murphy A, Prehn J, Murphy B
Exp Oncol . 2012 Oct; 34(3):192-9. PMID: 23070004
Most cells express a variety of both anti-apoptotic and pro-apoptotic Bcl-2 proteins and the interaction within this family dictates whether a cell survives or dies. The dysregulation of the anti-anti-apoptotic...
6.
Murphy A, Hill R
J Mater Sci Mater Med . 2004 Sep; 14(11):1011-5. PMID: 15348516
The hardness, fracture toughness, toughness, flexural strength and Young's moduli of three acrylic tooth polymers were investigated. The first polymer was based on a conventional homopolymer poly(methylmethacrylate). The second was...
7.
Zugaro L, Reid G, Ji H, Eddes J, Murphy A, Burgess A, et al.
Electrophoresis . 1998 Jun; 19(5):867-76. PMID: 9629929
Stathmin is a regulatory phosphoprotein that is a target for both cell cycle and cell surface receptor-regulated phosphorylation events. There are at least 14 isoforms of stathmin that migrate on...
8.
Srinivasan M, Rahmathullah R, BLAIR C, Murphy A, Beck R, Wilkins J, et al.
Br J Ophthalmol . 1998 Mar; 81(10):896-900. PMID: 9486033
Aims: The study was undertaken to test the feasibility of using the LOCS III cataract grading scale in the field and to determine the rate of cataract progression over a...
9.
Ward P, Higgins T, Murphy A, Mullan P, Rozengurt E, Lax A
FEBS Lett . 1994 Mar; 342(1):81-4. PMID: 8143855
Pasteurella multocida toxin (PMT) is a potent mitogen for Swiss 3T3 fibroblasts and cytotoxic to embryonic bovine lung cells. Site-directed mutagenesis was used to investigate the functional significance of a...
10.
Murphy A, Rozengurt E
J Biol Chem . 1992 Dec; 267(35):25296-303. PMID: 1334089
Treatment of Swiss 3T3 cells with a subsaturating concentration of recombinant Pasteurella multocida toxin (rPMT) markedly potentiated the production of inositol phosphates induced by bombesin, vasopressin, and endothelin but not...