A C Granholm
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Explore the profile of A C Granholm including associated specialties, affiliations and a list of published articles.
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80
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1223
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Recent Articles
1.
Lemoine L, Ledreux A, Mufson E, Perez S, Simic G, Doran E, et al.
Mol Neurodegener
. 2020 Nov;
15(1):68.
PMID: 33222700
Introduction: Tau pathology is a major age-related event in Down syndrome with Alzheimer's disease (DS-AD). Although recently, several different Tau PET tracers have been developed as biomarkers for AD, these...
2.
Delayed development of GFA immunoreactivity in the parietal cortex during thyroid hormone deficiency
Granholm A, Dahl D, Siegel R, Bjorklund H, Seiger A
Int J Dev Neurosci
. 2014 May;
3(2):149-56.
PMID: 24874596
The influence of neonatal hypothyroidism on the development of immunoreactivity to glial fibrillary acidic protein (GFA) was studied in parietal cortex of rats treated from birth with the antithyroid agent...
3.
Granholm A, Dahl D, Bjorklund H, Seiger A
Int J Dev Neurosci
. 2014 May;
3(1):33-40.
PMID: 24874491
Dependency of astrocytes on thyroid hormones during development was studied in intraocular cortex cerebri grafts, using antibodies to the glial fibrillary acidic protein (GFA). Fetal cortex cerebri was left in...
4.
Granholm A, Siegel R, Seiger A
Int J Dev Neurosci
. 2014 May;
2(4):337-45.
PMID: 24874144
Immature superior cervical ganglia and brain stem pieces containing 5-hydroxytryptamine neurons of the dorsal raphe nucleus were grafted to the anterior eye chamber of intact and thyroidectomized recipients. The grafts...
5.
Granholm A
Restor Neurol Neurosci
. 2011 May;
1(5):331-8.
PMID: 21551575
The effects of thyroid hormone deficiency on the noradrenergic innervation of hippocampus from locus coeruleus (LC) were examined using intraocular double transplants in albino rats. Fetal brainstem pieces containing the...
6.
Galantamine effects on memory, spatial cue utilization, and neurotrophic factors in aged female rats
French K, Bimonte-Nelson H, Granholm A
Cell Transplant
. 2007 May;
16(3):197-205.
PMID: 17503733
Galantamine is an acetylcholine esterase inhibitor that has been approved for use in Alzheimer's disease. However, even though clinical studies indicate efficacy in attenuating some of the symptoms associated with...
7.
Bickford P, Bowenkamp K, Taglialatela G, Hoertig G, Granholm A
Microsc Res Tech
. 2001 Aug;
54(5):309-16.
PMID: 11514987
Aging is associated with a decline in the function of beta-adrenergic receptor responses in the cerebellum. This decline in noradrenergic receptor sensitivity may underlie some of the accompanying age-related declines...
8.
Granholm A, Helt C, Srivastava N, Backman C, Gerhardt G
Microsc Res Tech
. 2001 Aug;
54(5):298-308.
PMID: 11514986
Recent studies have suggested that factors in the target tissue influence the degree of plasticity and regeneration following aging and/or specific insults. We have investigated whether young or aged targets...
9.
Helt C, Hoernig G, Albeck D, Gerhardt G, Ickes B, Reyland M, et al.
Exp Neurol
. 2001 Jul;
170(2):258-69.
PMID: 11476591
Transplantation of fetal ventral mesencephalic (VM) tissue shows great promise as an experimental therapy for patients with Parkinson's disease. However, cell survival in brain tissue grafts is poor, with survival...
10.
Palmer M, Granholm A, van Horne C, Giardina K, Freund R, Moorhead J, et al.
Brain Res
. 2001 Feb;
890(1):86-99.
PMID: 11164771
Parkinson's disease (PD) is characterized by a degeneration of the dopamine (DA) pathway from the substantia nigra (SN) to the basal forebrain. Prior studies in unilateral 6-hydroxydopamine (6-OHDA)-lesioned rats have...