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The Effects of Dental Disease on Systemic Disease

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Date 1998 Oct 21
PMID 9779540
Citations 11
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Abstract

Chronic exposure to periodontal pathogens results in the continued stimulation of an immune and nonimmune response by the host. The cytokines and other inflammatory mediators produced in gingivitis/periodontitis result in local tissue destruction and may reach significant levels affecting the cardiovascular system or placental tissues. The oral cavity may also serve as a direct reservoir for bacterial contamination of the lungs with subsequent development of bacterial pneumonia.

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