Topical Oral 1-tetradecanol Complex in the Treatment of Periodontal Diseases in Cats

Overview

Journal J Feline Med Surg

Specialty Veterinary Medicine

Date 2019 Jan 18

PMID 30652935

Citations 1

Authors

Fernanda Maria Lopes Kubitza

James Mudie George Anthony

Affiliations

Soon will be listed here.

Abstract

Objectives: The aim of this study was to evaluate the outcomes of the treatment of chronic periodontal disease with an oral application of tetradecanol complex (1-TDC) in cats.

Methods: The test group (n = 9) received 1-TDC (525 mg per gel capsule/day) and the placebo group (n = 4) received olive oil (0.25 ml per gel capsule/day) for 6 weeks.

Results: Oral treatment with 1-TDC resulted in significant reductions in all parameters of clinical periodontal disease except tooth mobility at 6 weeks. The 1-TDC group exhibited a statistically significant reduction in pocket depth, clinical attachment loss, gingival index and bleeding on probing after treatment at 6 weeks, whereas the placebo group did not show any significant change.

Conclusions And Relevance: Chronic inflammation associated with periodontal diseases leads to periodontal tissue destruction. As a result, modulation of the host response has been included in the treatment protocol for periodontal diseases. Fatty acids present anti-inflammatory properties and are being investigated for use in the treatment and prevention of progressive periodontal diseases.

Citing Articles

Dental Problems and Prophylactic Care in Cats-Knowledge and Perceptions among Swedish Cat Owners and Communication by Veterinary Care Staff.

Oskarsson K, Axelsson Puurtinen L, Penell J Animals (Basel). 2021; 11(9).

PMID: 34573537 PMC: 8469879. DOI: 10.3390/ani11092571.

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