Cell-mediated Immunity to Vibrio Cholerae with Ribonucleic Acid-protein Fractions of V. Cholerae L-form Lysates

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1976 Aug 1

PMID 971951

Citations 4

Authors

S C Agarwal

T Sundararaj

Affiliations

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Abstract

Different L-form lysate vaccines of Vibrio cholerae serotypes Ogawa and Inaba and their combination along with ethyl alcohol-precipitated ribonucleic acid (E-RNA) and phenol-extracted RNA (P-RNA) fractions of V. cholerae Ogawa lysates were tested for production of cell-mediated immunity. Both E-RNA and P-RNA fractions induced an increase in leukocyte migration inhibition, macrophage migration inhibition, and macrophage aggregation. They also induced delayed hypersensitivity in rabbits. More consistent results were obtained with the P-RNA fraction.

Citing Articles

Leucocyte migration inhibition with human heart valve glycoproteins and group A streptococcal ribonucleic acid proteins in rheumatic heart disease and post-streptococcal glomerulonephritis.

Gowrishankar R, Agarwal S Clin Exp Immunol. 1980; 39(2):519-25.

PMID: 6156043 PMC: 1538070.

Cell-mediated immunity after oral immunization with ribonucleic acid-protein fractions of Vibrio cholerae L-form lysates.

Agarwal S, Sundararaj T Infect Immun. 1977; 16(2):527-30.

PMID: 863514 PMC: 420986. DOI: 10.1128/iai.16.2.527-530.1977.

Cell-mediated immunity in experimental Nocardia asteroides infection.

Sundararaj T, Agarwal S Infect Immun. 1977; 15(2):370-5.

PMID: 321348 PMC: 421376. DOI: 10.1128/iai.15.2.370-375.1977.

Pathophysiological effects of Vibrio cholerae and enterotoxigenic Escherichia coli and their exotoxins on eucaryotic cells.

Richards K, Douglas S Microbiol Rev. 1978; 42(3):592-613.

PMID: 82199 PMC: 281445. DOI: 10.1128/mr.42.3.592-613.1978.

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