New Options for Diagnosing and Treating Acromegaly

Overview

Journal Cleve Clin J Med

Specialty General Medicine

Date 1998 Jul 29

PMID 9679389

Citations 2

Authors

A L Barkan

Affiliations

Soon will be listed here.

Abstract

Insulin-like growth factor 1 (IGF-1) is the final pathway of the growth hormone cascade, and is a better clinical measure of acromegaly than growth hormone itself. In patients with acromegaly, medical treatment with a somatostatin analog normalizes growth hormone and IGF-1 levels and produces clinical improvement quickly.

Citing Articles

Expression of neuropeptide hormone receptors in human adrenal tumors and cell lines: antiproliferative effects of peptide analogues.

Ziegler C, Brown J, Schally A, Erler A, Gebauer L, Treszl A Proc Natl Acad Sci U S A. 2009; 106(37):15879-84.

PMID: 19717419 PMC: 2733863. DOI: 10.1073/pnas.0907843106.

Cost-of-illness study in acromegalic patients in Italy.

Didoni G, Grottol S, Gasco V, Battistini M, Ferone D, Giusti M J Endocrinol Invest. 2005; 27(11):1034-9.

PMID: 15754735 DOI: 10.1007/BF03345306.