Mammalian Toxicity of Helenalin, the Toxic Principle of Helenium Microcephalum CD (smallhead Sneezeweed)

Overview

Journal Am J Vet Res

Specialty Veterinary Medicine

Date 1976 Jul 1

PMID 937811

Citations 5

Authors

D A WITZEL

W Ivie

J W DOLLAHITE

Affiliations

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Abstract

Studies with smallhead sneezeweed (Helenium microcephalum DC) indicated that a sesquiterpene lactone, helenalin, is the only significant toxic constituent present. The oral median lethal dose of helenalin for 5 mammalian species was between 85 and 105 mg/kg.

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