Malignant Evolution of Presumed Benign Lesions in the Brain in Neurofibromatosis: Case Report

We report a patient suffering from neurofibromatosis type 1 in whom neoplasms developed from the areas of altered signal which are generally considered benign and typical of the disease. MRI, despite two previous examinations 3 and 2 years before development of the tumour, gave no clue to an unfavourable outcome.