Single-particle Tracking: Applications to Membrane Dynamics

Overview

Journal Annu Rev Biophys Biomol Struct

Publisher Annual Reviews

Specialties Biophysics
Molecular Biology

Date 1997 Jan 1

PMID 9241424

Citations 608

Authors

M J Saxton

K Jacobson

Affiliations

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Abstract

Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.

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