Does Fluorine-18 Fluorodeoxyglucose Metabolic Imaging of Tumours Benefit Oncology?

Overview

Journal Eur J Nucl Med

Specialty Nuclear Medicine

Date 1997 Jun 1

PMID 9169580

Citations 13

Authors

C S Brock

S R Meikle

P Price

Affiliations

Soon will be listed here.

Abstract

Fluoro-deoxyglucose (FDG) is a metabolic marker, which follows the same route into cells as that of glucose, and it can be radiolabelled with fluorine-18, 18F-FDG making it suitable for imaging with positron emission tomography (PET). The fact that rapidly proliferating cells such as tumour cells accumulate 18F-FDG more avidly than those with a normal turnover rate has given rise to its potential in oncology. The rationale and previous published uses of 18F-FDG in oncology are reviewed, together with the various analysis techniques and associated methodological difficulties.

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