Functional Relationship Between Escherichia Coli RNase E and the CafA Protein

Overview

Journal Mol Gen Genet

Specialties Genetics
Molecular Biology

Date 1997 Jan 27

PMID 9037114

Citations 27

Authors

M Wachi

G Umitsuki

K Nagai

Affiliations

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Abstract

We analyzed the functional relationship between the Escherichia coli RNase E and the CafA protein, which show extensive sequence similarity. The temperature-sensitive growth of the RNase E mutant strain ams1 was partially suppressed by multicopy plasmids bearing the cafA gene. Introduction of a cafA::cat mutation enhanced the temperature sensitivity of the ams1 mutant. These results suggest that there is a functional homology between these two proteins.

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