Simple Method for Elimination of Aminoglycosides from Serum to Permit Bioassay of Other Antimicrobial Agents

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1977 Aug 1

PMID 900922

Citations 24

Authors

P Stevens

L S Young

Affiliations

Soon will be listed here.

Abstract

Cellulose phosphate powder can be added to serum to selectively bind aminoglycosides by ionic interaction without binding or inactivation of the penicillins, the cephalosporins, clindamycin, vancomycin, chloramphenicol, or trimethoprim. This simple, rapid technique permits the measurement of non-aminoglycoside antibiotics in the presence of aminoglycosides.

Citing Articles

Evaluation of a novel fluorescence polarization immunoassay for teicoplanin.

Cox H, Whitby M, Nimmo G, Williams G Antimicrob Agents Chemother. 1993; 37(9):1924-6.

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Assay of antibiotics when used therapeutically in combination with aminoglycosides.

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PMID: 7396476 DOI: 10.1007/BF00422241.

Comparative pharmacokinetics of ceforanide (BL-S786R) and cefazolin in laboratory animals and humans.

Lee F, Pfeffer M, Van Harken D, Smyth R, Hottendorf G Antimicrob Agents Chemother. 1980; 17(2):188-92.

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Synergism between aminoglycosides and cephalosporins with antipseudomonal activity: interaction index and killing curve method.

Hallander H, Dornbusch K, Gezelius L, Jacobson K, Karlsson I Antimicrob Agents Chemother. 1982; 22(5):743-52.

PMID: 7181485 PMC: 185655. DOI: 10.1128/AAC.22.5.743.

Inactivation of amikacin and gentamicin by carbenicillin in patients with end-stage renal failure.

Blair D, Duggan D, Schroeder E Antimicrob Agents Chemother. 1982; 22(3):376-9.

PMID: 7137981 PMC: 183751. DOI: 10.1128/AAC.22.3.376.

References

Lietman P, White T, Shaw W . Chloramphenicol: an enzymological microassay. Antimicrob Agents Chemother. 1976; 10(2):347-53. PMC: 429746. DOI: 10.1128/AAC.10.2.347. View

Winters R, Litwack K, HEWITT W . Relation between dose and levels of gentamicin in blood. J Infect Dis. 1971; 124 Suppl:S90-5. DOI: 10.1093/infdis/124.supplement_1.s90. View

Edberg S, Bottenbley C, Gam K . Use of sodium polyanethol sulfonate to selectively inhibit aminoglycoside and polymyxin antibiotics in a rapid blood level antibiotic assay. Antimicrob Agents Chemother. 1976; 9(3):414-7. PMC: 429545. DOI: 10.1128/AAC.9.3.414. View

Louie T, Tally F, Bartlett J, Gorbach S . Rapid microbiological assay for chloramphenicol and tetracyclines. Antimicrob Agents Chemother. 1976; 9(6):874-8. PMC: 429642. DOI: 10.1128/AAC.9.6.874. View

Sabath L, CASEY J, Ruch P, Stumpf L, FINLAND M . Rapid microassay of gentamicin, kanamycin, neomycin, streptomycin, and vancomycin in serum or plasma. J Lab Clin Med. 1971; 78(3):457-63. View