Inhibitors of Endothelin

Overview

Journal Med Res Rev

Publisher Wiley

Specialties General Medicine
Pharmacology

Date 1997 Jan 1

PMID 8979248

Citations 5

Authors

M L Webb

T D Meek

Affiliations

Soon will be listed here.

Abstract

With the advent of the first generation of both selective and nonselective endothelin antagonists being a relatively recent event, the manifold therapeutic potentials of these compounds are only now being explored clinically. Undoubtedly, numerous clinical utilities for these compounds will soon be realized.

Citing Articles

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PMID: 35530510 PMC: 9075737. DOI: 10.3389/fphys.2022.848867.

Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels.

Lu J, Aguilar A, Zou B, Bao W, Koldas S, Shi A Bioorg Med Chem. 2015; 23(17):5985-98.

PMID: 26190460 PMC: 4555001. DOI: 10.1016/j.bmc.2015.06.055.

Endothelin-1 and diabetic complications: focus on the vasculature.

Ergul A Pharmacol Res. 2011; 63(6):477-82.

PMID: 21292003 PMC: 7383935. DOI: 10.1016/j.phrs.2011.01.012.

Endothelin-1, big endothelin-1, and nitric oxide in patients with chronic renal disease and hypertension.

Mikulic I, Petrik J, Galesic K, Romic Z, cepelak I, Zeljko-Tomic M J Clin Lab Anal. 2009; 23(6):347-56.

PMID: 19927348 PMC: 6648951. DOI: 10.1002/jcla.20324.

Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: modulation by simultaneous ET(B) receptor activation.

Piovezan A, DOrleans-Juste P, Souza G, Rae G Br J Pharmacol. 2000; 129(5):961-8.

PMID: 10696096 PMC: 1571931. DOI: 10.1038/sj.bjp.0703154.