Synthesis and Reactions of Some New 4H-pyrano[3,2-c]benzopyran-5-one Derivatives and Their Potential Biological Activities

Overview

Journal Pharmazie

Specialties Pharmacology
Pharmacy

Date 1996 Mar 1

PMID 8900865

Citations 11

Authors

R M Shaker

Affiliations

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Abstract

Several new 4H-pyrano[3,2-c]benzopyran-5-ones (6a-g and 10) which exhibited antibacterial and fungicidal activity, have been synthesized via a one flask multicomponent condensation of aldehydes with malononitrile and 4-hydroxycoumarin. The reactions of 6a with several nucleophilic reagents are reported.

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