Fractional Flux Rates of Nt-methylhistidine in Skin and Gastrointestine: the Contribution of These Tissues to Urinary Excretion of Nt-methylhistidine in the Rat

Overview

Journal Br J Nutr

Specialty Nutritional Sciences

Date 1977 Jul 1

PMID 889769

Citations 15

Authors

N Nishizawa

T Noguchi

S Hareyama

R Funabiki

Affiliations

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Abstract

1. Fractional flux rates of Ntau-methylhistidine (3-methylhistidine; Me-His) of skin and gastrointestine were measured by administering [methyl-3H]methionine to rats. 2. The results showed that the contribution of these tissues to urinary excretion of Me-His was at least 16-6%. This means that when fractional catabolic rates of myosin and actin were estimated from urinary excretion of Me-His, the part of Me-His derived from skin and gastrointestine should not be neglected.

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