Enlarged Dysmorphic Lysosomes in an Established Beige (C57BL/6J;bgJ(/bgJ)) Mouse Mutant Fibroblast Line: a Reversible Characteristic

Overview

Journal In Vitro Cell Dev Biol Anim

Publisher Springer

Specialties Biology
Cell Biology

Date 1996 Sep 1

PMID 8889598

Authors

J B Gow

T A Lyerla

S Lainwala

Affiliations

Soon will be listed here.

References

Swank R, Reddington M, Howlett O, NOVAK E . Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha. Blood. 1991; 78(8):2036-44. View

Clawson C, White J, Repine J . The Chédiak-Higashi syndrome. Evidence that defective leukotaxis is primarily due to an impediment by giant granules. Am J Pathol. 1978; 92(3):745-53. PMC: 2018262. View

Hearing V, Phillips P, LUTZNER M . The fine structure of melanogenesis in coat color mutants of the mouse. J Ultrastruct Res. 1973; 43(1):88-106. DOI: 10.1016/s0022-5320(73)90072-5. View

Oliver J . Impaired microtubule function correctable by cyclic GMP and cholinergic agonists in the Chediak-Higashi syndrome. Am J Pathol. 1976; 85(2):395-418. PMC: 2032559. View

Swank R, Sweet H, Davisson M, Reddington M, NOVAK E . Sandy: a new mouse model for platelet storage pool deficiency. Genet Res. 1991; 58(1):51-62. DOI: 10.1017/s0016672300029608. View

NOVAK E, Hui S, Swank R . Platelet storage pool deficiency in mouse pigment mutations associated with seven distinct genetic loci. Blood. 1984; 63(3):536-44. View

Frankel F, Tucker R, BRUCE J, Stenberg R . Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables. J Cell Biol. 1978; 79(2 Pt 1):401-8. PMC: 2110259. DOI: 10.1083/jcb.79.2.401. View

Perou C, Kaplan J . Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility. J Cell Sci. 1993; 106 ( Pt 1):99-107. DOI: 10.1242/jcs.106.1.99. View

Davis W, Douglas S . Defective granule formation and function in the Chediak-Higashi syndrome in man and animals. Semin Hematol. 1972; 9(4):431-50. View

10.

LOREZ H, Da Prada M . Fluorescence microscopical study of 5-hydroxytryptamine storage organelles in mepacrine-incubated blood platelets of beige mice (Chediak-Higashi syndrome). Experientia. 1978; 34(5):663-4. DOI: 10.1007/BF01937020. View

11.

Mithieux G, Rousset B . Identification of a lysosome membrane protein which could mediate ATP-dependent stable association of lysosomes to microtubules. J Biol Chem. 1989; 264(8):4664-8. View

12.

Willingham M, SPICER S, Vincent Jr R . The origin and fate of large dense bodies in beige mouse fibroblasts. Lysosomal fusion and exocytosis. Exp Cell Res. 1981; 136(1):157-68. DOI: 10.1016/0014-4827(81)90047-1. View

13.

Roder J, Duwe A . The beige mutation in the mouse selectively impairs natural killer cell function. Nature. 1979; 278(5703):451-3. DOI: 10.1038/278451a0. View

14.

Silverstein S, Wang E . Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages. J Cell Biol. 1980; 86(2):641-55. PMC: 2111499. DOI: 10.1083/jcb.86.2.641. View

15.

Gow J, Lainwala S, Lyerla T . Cellular expression of the beige mouse mutation and its correction in hybrids with control human fibroblasts. In Vitro Cell Dev Biol Anim. 1993; 29A(11):884-91. DOI: 10.1007/BF02631368. View

16.

Gallin J, Bujak J, Patten E, Wolff S . Granulocyte function in the Chediak-Higashi syndrome of mice. Blood. 1974; 43(2):201-6. View

17.

Root R, Rosenthal A, Balestra D . Abnormal bactericidal, metabolic, and lysosomal functions of Chediak-Higashi Syndrome leukocytes. J Clin Invest. 1972; 51(3):649-65. PMC: 302171. DOI: 10.1172/JCI106854. View

18.

Roder J, Haliotis T, Laing L, Kozbor D, Rubin P, Pross H . Further studies of natural killer cell function in Chediak-Higashi patients. Immunology. 1982; 46(3):555-60. PMC: 1555330. View

19.

Scheel J, Kreis T . Motor protein independent binding of endocytic carrier vesicles to microtubules in vitro. J Biol Chem. 1991; 266(27):18141-8. View

20.

White J, Krumwiede M . Normal-sized primary lysosomes are present in Chediak-Higashi syndrome neutrophils. Pediatr Res. 1987; 22(2):208-15. DOI: 10.1203/00006450-198708000-00022. View