Sister Chromatid Exchanges in Balanced Translocation Carriers and in Patients with Unbalanced Karyotypes

Overview

Journal Hum Genet

Specialty Genetics

Date 1977 Jun 10

PMID 881193

Citations 2

Authors

C Stoll

D S Borgaonkar

P BIGEL

Affiliations

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Abstract

Sister chromatid exchanges (SCEs) were studied in peripheral human leukocytes from 16 patients with balanced translocations or with unbalanced karyotypes, and from 4 controls. No difference was seen between these two groups of people in the mean number of SCEs per cell, or in the total number of SCEs observed for each pair of autosomes involved in the translocations studied. With this last number no difference from the expected number of SCEs, if one supposes that SCEs follow a random distribution, was seen.

Citing Articles

Sister chromatid exchanges and heterochromatin.

Schubert I, Rieger R Hum Genet. 1981; 57(2):119-30.

PMID: 6785204 DOI: 10.1007/BF00282006.

Frequency of sister chromatid exchanges in a balanced reciprocal whole-arm translocation.

Schober A, Fonatsch C, Schober O Hum Genet. 1979; 51(1):93-7.

PMID: 500097 DOI: 10.1007/BF00278297.

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