Cytological Detection of Mutagen-carcinogen Exposure by Sister Chromatid Exchange

Overview

Journal Nature

Specialty Science

Date 1975 Nov 13

PMID 52847

Citations 185

Authors

P Perry

H J Evans

Affiliations

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Abstract

A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens-carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens.

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