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Experimental Rejection of a Nonadaptive Explanation for Increased Cell Size in Escherichia Coli

Overview
Journal J Bacteriol
Publisher American Society for Microbiology
Specialty Microbiology
Date 1996 Sep 1
PMID 8752359
Citations 18
Authors
J A Mongold
R E Lenski
Affiliations
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Abstract

Populations of Escherichia coli that have been serially propagated for thousands of generations in glucose minimal medium show heritable increases in both cell size and growth rate. We sought to test the hypothesis that the increased cell size of the derived genotypes could be explained solely by their faster growth. The regression of cell size on growth rate differed significantly between populations having ancestral and derived genotypes, with the latter producing larger cells over almost the entire range of growth rates. Thus, the physiological coupling between cell size and growth rate has been evolutionarily altered.

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References
1.
Gould S, Lewontin R . The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme. Proc R Soc Lond B Biol Sci. 1979; 205(1161):581-98. DOI: 10.1098/rspb.1979.0086. View
2.
Akerlund T, Nordstrom K, Bernander R . Analysis of cell size and DNA content in exponentially growing and stationary-phase batch cultures of Escherichia coli. J Bacteriol. 1995; 177(23):6791-7. PMC: 177544. DOI: 10.1128/jb.177.23.6791-6797.1995. View
3.
Schaechter M, MAALOE O, KJELDGAARD N . Dependency on medium and temperature of cell size and chemical composition during balanced grown of Salmonella typhimurium. J Gen Microbiol. 1958; 19(3):592-606. DOI: 10.1099/00221287-19-3-592. View
4.
Travisano M, Lenski R . Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptation. Genetics. 1996; 143(1):15-26. PMC: 1207249. DOI: 10.1093/genetics/143.1.15. View
5.
Elena S, Cooper V, Lenski R . Punctuated evolution caused by selection of rare beneficial mutations. Science. 1996; 272(5269):1802-4. DOI: 10.1126/science.272.5269.1802. View