Characterisation of a Helicobacter Pylori Phage (HP1)

Overview

Journal J Med Microbiol

Specialty Microbiology

Date 1993 Apr 1

PMID 8474115

Citations 17

Authors

E Heintschel von Heinegg

H P Nalik

E N Schmid

Affiliations

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Abstract

The infection of two Helicobacter pylori strains with a phage-containing supernate of the lysogenic H. pylori strain IMMi 290/89 resulted in a lytic cycle and propagation of phage HP1. In negatively-stained preparations, the empty phage heads measured 55-60 nm in diameter and mature heads measured 50 nm. The flexible, striated phage tail was c. 170 nm in length and 9.5 nm in diameter. The phage showed a mean density of 1.40 g/cm3 in sucrose-density gradients and contained double-stranded DNA c. 22,000 bp in length.

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