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Investigation of the Pseudomonas Aeruginosa AmpR Gene and Its Role at the Chromosomal AmpC Beta-lactamase Promoter

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Specialty Microbiology
Date 1993 Aug 1
PMID 8405939
Citations 30
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Abstract

The complete sequence of the Pseudomonas aeruginosa beta-lactamase regulator gene ampR has been determined. The amino acid sequence encoded by this gene is compared with other members of the LysR family of transcription factors. The P. aeruginosa ampC promoter was subcloned and gel mobility shift assays were used to demonstrate specific binding of AmpR to the ampC promoter region.

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