Whole-mount in Situ Hybridization in the Mouse Embryo: Gene Expression in Three Dimensions

Overview

Journal Trends Genet

Specialty Genetics

Date 1993 May 1

PMID 8337752

Citations 41

Authors

B Rosen

R S Beddington

Affiliations

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Abstract

Non-isotopic whole-mount in situ hybridization of mRNA is a novel technique that has greatly facilitated the precise three-dimensional localization of transcripts from genes whose expression is important during development. This methodology has recently been applied to the study of the mouse embryo and offers particular advantages over conventional procedures.

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