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What Would Be Conserved if "the Tape Were Played Twice"?

Overview
Journal Proc Natl Acad Sci U S A
Specialty Science
Date 1994 Jan 18
PMID 8290596
Citations 21
Authors
W Fontana
L W Buss
Affiliations
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Abstract

We develop an abstract chemistry, implemented in a lambda-calculus-based modeling platform, and argue that the following features are generic to this particular abstraction of chemistry; hence, they would be expected to reappear if "the tape were run twice": (i) hypercycles of self-reproducing objects arise; (ii) if self-replication is inhibited, self-maintaining organizations arise; and (iii) self-maintaining organizations, once established, can combine into higher-order self-maintaining organizations.

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References
1.
Eigen M . Selforganization of matter and the evolution of biological macromolecules. Naturwissenschaften. 1971; 58(10):465-523. DOI: 10.1007/BF00623322. View
2.
Kauffman S . Autocatalytic sets of proteins. J Theor Biol. 1986; 119(1):1-24. DOI: 10.1016/s0022-5193(86)80047-9. View