Waves and Stimulus-modulated Dynamics in an Oscillating Olfactory Network

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1994 Jan 18

PMID 8290580

Citations 40

Authors

K R Delaney

A Gelperin

M S Fee

J A Flores

R Gervais

D W Tank

D Kleinfeld

Affiliations

Soon will be listed here.

Abstract

The temporal dynamics of electrical activity in an olfactory organ, the procerebral lobe of the terrestrial mollusc Limax maximus, is studied. The lobe exhibits intrinsic oscillations in its field potential. Intracellular recordings show that the lobe contains two classes of neurons, both with activity phase-locked to the oscillation. Neurons in one class produce periodic bursts of spikes while those in the other class fire infrequently but receive strong, periodic inhibition whose onset coincides with the burst. The large-scale activity of these neurons is imaged in preparations stained with voltage-sensitive dyes. We observe waves of electrical activity that span the width of the lobe and travel its full length along a longitudinal axis. Simultaneous optical and intracellular recordings show that the form of the wave reflects the electrical activity of both classes of neurons. The application of natural odor stimuli causes the electrical activity along the lobe to transiently switch from the state with propagating waves to one with spatially uniform oscillations. The behavioral and computational relevance of this change in global timing is discussed.

Citing Articles

Distribution and physiological effect of enterin neuropeptides in the olfactory centers of the terrestrial slug Limax.

Matsuo R, Kobayashi S, Furuta A, Osugi T, Takahashi T, Satake H J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020; 206(3):401-418.

PMID: 31996989 DOI: 10.1007/s00359-020-01400-2.

Do terrestrial gastropods use olfactory cues to locate and select food actively?.

Kiss T Invert Neurosci. 2017; 17(3):9.

PMID: 28688004 DOI: 10.1007/s10158-017-0202-2.

Phase-Dependent Modulation of Oscillatory Phase and Synchrony by Long-Lasting Depolarizing Inputs in Central Neurons.

Watanabe S, Hirono M eNeuro. 2016; 3(5).

PMID: 27785464 PMC: 5069685. DOI: 10.1523/ENEURO.0066-16.2016.

Nitric Oxide-Mediated Modulation of Central Network Dynamics during Olfactory Perception.

Watanabe S, Takanashi F, Ishida K, Kobayashi S, Kitamura Y, Hamasaki Y PLoS One. 2015; 10(9):e0136846.

PMID: 26360020 PMC: 4567279. DOI: 10.1371/journal.pone.0136846.

Measuring predictability of autonomous network transitions into bursting dynamics.

Mofakham S, Zochowski M PLoS One. 2015; 10(4):e0122225.

PMID: 25855975 PMC: 4391948. DOI: 10.1371/journal.pone.0122225.

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