Mutations in the Delta Subunit Influence the Assembly of F1F0 ATP Synthase in Escherichia Coli

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1994 Jan 1

PMID 8288552

Citations 4

Authors

A E Stack

B D Cain

Affiliations

Soon will be listed here.

Abstract

Missense mutations affecting Asp-161 and Ser-163 in the delta subunit of F1F0 ATP synthase have been generated. Although most substitutions allowed substantial enzyme function, the delta Asp-161-->Pro substitution resulted in a loss of enzyme activity. The loss of activity was attributable to a structural failure altering assembly of the enzyme complex.

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