Vasoconstrictors in Local Anesthesia for Dentistry

Overview

Journal Anesth Prog

Specialties Anesthesiology
Dentistry

Date 1993 Jan 1

PMID 8250339

Citations 17

Authors

A L Sisk

Affiliations

Soon will be listed here.

Abstract

Addition of a vasoconstrictor to a local anesthetic may have several beneficial effects: a decrease in the peak plasma concentration of the local anesthetic agent, increase in the duration and the quality of anesthesia, reduction of the minimum concentration of anesthetic needed for nerve block, and decrease of blood loss during surgical procedures. The addition of a vasoconstrictor to a local anesthetic may also have detrimental effects. A review of the literature indicates that vasoconstrictor concentrations in local anesthetics marketed for dental use in the United States are not always optimal to achieve the purposes for which they are added. In most cases, a reduced concentration of vasoconstrictor could achieve the same goal as the marketed higher concentration, with less side-effect liability.

Citing Articles

Effectiveness of Lidocaine with Epinephrine Irrigation in Reducing Acute Pain from Surgical Removal of Mesioangular-Impacted Third Molars.

Chatupos V, Apiphathanamontri M, Yuthavong S, Chatiketu P, Hutachok N, Srichairatanakool S Dent J (Basel). 2024; 12(12).

PMID: 39727469 PMC: 11674364. DOI: 10.3390/dj12120412.

Sustained release local anesthetics for pain management: relevance and formulation approaches.

Getachew M, Tesfaye H, Yihunie W, Ayenew T, Alemu S, Dagnew E Front Pain Res (Lausanne). 2024; 5:1383461.

PMID: 38645568 PMC: 11026556. DOI: 10.3389/fpain.2024.1383461.

Efficacy of inferior alveolar nerve block and intraligamentary anesthesia in the extraction of primary mandibular molars: A randomized controlled clinical trial.

Orafi M, Abd Elmunem H, Krishnaraaj S Saudi Dent J. 2023; 35(5):567-573.

PMID: 37520609 PMC: 10373082. DOI: 10.1016/j.sdentj.2023.05.011.

Effect of Local Anaesthesia with and without Adrenaline on Blood Glucose Concentration in Patients Undergoing Tooth Extractions - A Comparative Study.

Sunil Nair V, Anusuya N, Sankar K, Sathiyanathan D, Sane V, Kanagasabapathy T Ann Maxillofac Surg. 2023; 12(2):123-127.

PMID: 36874768 PMC: 9976855. DOI: 10.4103/ams.ams_136_22.

Anesthetic efficacies of buccal with palatal injection versus buccal with intra-septal injection in permanent maxillary first molars of pediatric patients.

Areenoo P, Manmontri C, Chaipattanawan N, Chompu-Inwai P, Khanijou M, Kumchai T J Dent Anesth Pain Med. 2022; 22(4):239-254.

PMID: 35991357 PMC: 9358269. DOI: 10.17245/jdapm.2022.22.4.239.

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