Adoptive Transfer of Polyclonal and Cloned Cytolytic T Lymphocytes (CTL) Specific for Mouse AIDS-associated Tumors is Effective in Preserving CTL Responses: a Measure of Protection Against LP-BM5 Retrovirus-induced Immunodeficiency

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1994 Jul 1

PMID 8207844

Citations 3

Authors

W R Green

K A Green

K M Crassi

Affiliations

Soon will be listed here.

Abstract

Cytolytic T lymphocytes (CTL) can be raised against C57BL/6 B-cell lymphomas from mice with LP-BM5 murine leukemia virus-induced AIDS (MAIDS). Adoptive transfer of polyclonal anti-MAIDS tumor CTL or two CTL clones specific for the B6-1710 MAIDS lymphoma caused preservation of major histocompatibility complex-restricted and allogeneic CTL responses, which may be interpreted as indices of protection from LP-BM5 murine leukemia virus-induced immunodeficiency.

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