Chemical Composition and Turnover of Peptidoglycan in Neisseria Gonorrhoeae

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1976 Jun 1

PMID 820685

Citations 43

Authors

B H Hebeler

F E Young

Affiliations

Soon will be listed here.

Abstract

The peptidoglycan of all four colonial types of a number of strains of Neisseria gonorrhoeae constituted 1 to 2% of the dry weight of the cell. The chemical composition of cell types examined was similar with molar ratios of 1:1:2:1:1 for muramic acid, glucosamine, alanine, glutamic acid, and diaminopimelic acid, respectively. Ninety-six percent of the mass of the peptidoglycan was composed of these compounds. A lipoprotein analogous to that observed in Escherichia coli was not detected. The chain length of the glycan varied from 80 to 110 disaccharide units. The peptide contained equimolar amounts of D- and L-alanine. The rate of turnover of peptidoglycan in strain RD5 was 50% per generation. Turnover proceeded without a lag and followed first-order kinetics.

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