Pharmacokinetic Considerations in Rational Drug Design
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References
1.
Lund Laursen A, Gerlach J
. Antipsychotic effect of remoxipride, a new substituted benzamide with selective antidopaminergic activity. Acta Psychiatr Scand. 1986; 73(1):17-21.
DOI: 10.1111/j.1600-0447.1986.tb02659.x.
View
2.
Stella V, Charman W, Naringrekar V
. Prodrugs. Do they have advantages in clinical practice?. Drugs. 1985; 29(5):455-73.
DOI: 10.2165/00003495-198529050-00002.
View
3.
Fuhr U, Strobl G, Manaut F, Anders E, Sorgel F, Chu D
. Quinolone antibacterial agents: relationship between structure and in vitro inhibition of the human cytochrome P450 isoform CYP1A2. Mol Pharmacol. 1993; 43(2):191-9.
View
4.
Sjoberg P, Olofsson I, Lundqvist T
. Validation of different microdialysis methods for the determination of unbound steady-state concentrations of theophylline in blood and brain tissue. Pharm Res. 1992; 9(12):1592-8.
DOI: 10.1023/a:1015816509140.
View
5.
BOHNI E, FUST B, Rieder J, SCHAERER K, Havas L
. Comparative toxicological, chemotherapeutic and pharmacokinetic studies with sulphormethoxine and other sulphonamides in animals and man. Chemotherapy. 1969; 14(4):195-226.
DOI: 10.1159/000220630.
View