Oocytes from Pachytene to Dictyotene Can Easily Be Analysed in Neonatal Rodents
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We have investigated the dynamics of meiotic prophase I in neonatal ovaries from different wild rodent species, from a laboratory strain of Mus musculus and from Mus musculus x Mus spretus F1 hybrids. We found that almost all stages of prophase I were regularly present in neonatal ovaries from these species and that their transcriptional activity can be assessed by [3H]-uridine incorporation, indicating that postnatal analysis of meiotic chromosomes and synapsis may be conducted as an alternative to the investigation of foetal ovaries.
Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one.
Ghafari F, Gutierrez C, Hartshorne G BMC Dev Biol. 2007; 7:87.
PMID: 17650311 PMC: 1965470. DOI: 10.1186/1471-213X-7-87.